Addiction Medicine Flashcards
unhealthy substance use in what two levels
pre-disease and disease
need to intervene at pre-disease
addiction is like other chronic diseases?
yes
initial substance use is chronic?
NO – THIS IS A CHOICE
what is one of the most addictive drugs?
percentages?
nicotine
76% have tried
20% have addiction in entire population
do all users become addicted?
what contributes?
heavy use and early use will increase addiction
about 25% of users become addicted
alcohol risky behavior
defined in men or woman?
men – 5 or more drinks in a day / over 14 in a week
woman – 4 or more a day or greater than 7 drinks in a week (includes men over 65 years of age)
1 drink is?
12 oz beer
5 oz wine
1.5 oz liquor
breakdown / criteria for substance use disorder
number for each category?
mild 2-4
moderate 4-5
severe 6 or more
so only need two of these to be diagnosed with moderate
drugs of abuse do what to the brain?
CHANGE THE BRAIN
- can see where in the brain they act and it is on the REWARD PATHWAY
reward pathway
dopaminergic system
This is a necessary pathway for our lives
- endorphines turn it on
what are two physiological adaptions to chronic opoid exposure
tolerance
physical dependence
tolerance
increased dosage needed to produce specific effect
- develops readily for CNS and respiratory depression
stimulants effect on dental? systemics?
teeth ground down, cracked, or loosened due to clenching or grinding; dry mouth; acids eat away at prtoective enamel
sores inside the mouth
systemics – chest pain/ myocardial infarction, kidney injury, stroke
stimulants effect on dental? systemics?
teeth ground down, cracked, or loosened due to clenching or grinding; dry mouth; acids eat away at prtoective enamel
sores inside the mouth
systemics – chest pain/ myocardial infarction, kidney injury, stroke
nicotine impact on dental
associated with increased pocket depth, loss of periodontal attachment, alveolar bone, and higher rate of tooth loss
dental procedures jsutifying prohpylaxis?
Manipulation of gingival tissues or periapical regions of teeth (cleaning, extractions, suture removal, biopsies, placement of orthodontic bands)
assessing treatment effectiveness in hypertension tx vs addiction tx?
hypertension – it works
addiction – it works IF THEY STAY ON THE TX
about how long tx for addiction for them to overcome?
about 85%
Buprenorphine is?
an FDA approved medicine to fight opoids
this is a partial agonist
FDA approved medicine for cocaine and methamphetamine?
currently there are no FDA approved
for tx of opoid can you prescribe methadone?
no – only in a clininc
goals for using medications for opiod use disroders?
- alleviate physical withdrawal
- opoid blockade
- alleviate drug craving
- normalized neurochemistry
buprenorphine is what type of treatment?
life sustaining
- proven in study
describe altered pain experience in users?
- patients with active opoid disorder have less pain tolerance than peers
- history of use have less pain tolerance
- patients on medication for opoid use disorders have less pain tolerance