addiction Flashcards
describing addiction- physical dependence
-occurs when a withdrawal symptom is produced by stopping
-only possible to establish someone is physically dependent when;
-they abstain from it
-withdrawal symptoms are apparent
describing addiction- psychological dependence
-refers to compulsion to experience effects of a substance for
-increase in pleasure or
-reduction in discomfort
psychological dependence leads to the substance becoming a habit despite harmful consequences
describing addiction- tolerance
-greater doses needed for same effect, this means greater doses needed to produce same effects on behaviour
-tolerance caused by repeated exposure
-behavioural tolerance- learns through experience to adjust their behaviour to compensate for effects of a substance
-cross tolerance- developing tolerance to one substance can reduce sensitivity to another
describing addiction- withdrawal symptoms
-symptoms associated with abstaining or reducing use
-opposite of symptoms created by substance
-indicated physical dependence
-motivation to take substance is partially to avoid these symptoms
-phase1- acute withdrawal within hours, intense cravings
-phase2- prolonged withdrawal over months or years, high sensitivity to cues
risk factors for addiction, 5
1.genetic vulnerability
2.stress
3.personality
4.family influences
5.peers
risk factors in development of addiction- genetic vulnerability
-low dopamine associated with addiction
-low D2 receptors inherited, people compensate by engaging in addictive behaviour
-genetic, environment interaction
-no one can become addicted if not exposed to situation
-someone does not inherit a addiction but a predisposition
risk factors- stress
‘perceived inability to cope’
-increased stress means increased vulnerability to addiction
-maladaptive coping e.g. drinking
-likely that chronic stress or trauma can lead to vulnerability
-stress of quitting or paying for addiction creates more
risk factors- personality
-no generally addictive personality, but most people with APD are addicted substance abusers
-APD means a person breaks social norms, is impulsive and behave criminally to satisfy desires
-almost inevitable they try substances (robins 1998)
risk factors- family influences
-perceived parental approval- pos attitudes towards drug or behaviour such as gambling
-adolescents who perceive parents to have little or more interest in monitoring their behaviour are more likely to develop addiction
-SLT- exposure is also a factor, more likely to start if it is normal part of their everyday
risk factors- peers
-SLT- childhood
O’connell suggested 3 major factors to alcohol addiction;
-attitudes about drinking by associating with peers who drink
-peers provide opportunity
-overestimate how much peers are drinking in attempt to keep up with perceived norm
brain neurochemistry in exp for nicotine addiction
-Dani and Heinemann 1996 focused on dopamine in their desensitisation hypothesis of nicotine addiction
exp for nicotine addiction- brain neurochem- nAChRs and dopamine
-ACh is a key neurotransmitter in the CNS
-one special subtype is nAChR acitvated by ACh or nicotine
-nAChRs are stimulated and transmit dopamine
-then they are immediately shut down and temporarily cannot respond to neurotransmitters
exp for nicotine addiction- brain neurochem-operant conditioning
-creating a pleasurable effect
-nAChRs are concentrated in VTA
-dopamine transmitted along 2 pathways
1.mesolimbic pathway
2.mesocortical pathway
-both release dopamine into frontal cortex
-pleasurable effects due to dopamine reward system become associated with smoking through operant conditioning
exp for nicotine addiction- brain neurochem-withdrawl
-when not smoking e.g. over night nicotine disappears from body and nAChRs become functional again-resensitised and upregulated
-nAChRs now overstimulated by ACh and at their most sensitive
-first cigarette of the day is the best as it strongly activates dopamine reward system
exp for nicotine addiction- brain neurochem-dependence
-unpleasent withdrawl symptoms are avoided by having another cigarette
-this means a constant cycle of daytime downregulation and night time upregulation creating long term desensitisation of nAChRs
exp for nicotine addiction- brain neurochem-tolerance
-continuous exposure to nicotine causes permanent changes to brain neurochemistry
-tolerance develops as smoker needs more nicotine for same effect