ADD Transport into mitochondria + peroxisomes

Question 1

What is the function of the mitochondria?

Answer 1

-energy production by making large amounts of ATP
-produces a H+ grad across the inner mito membrane, which drives ATPase
-plays a key role in apoptosis

Question 2

Describe the outer membrane of mitochondria

Answer 2

-perforated with large channels (porins)
-allow entry of molecules < 5000 kDa
-contains enzymes involved in mitochondrial lipid synthesis

Question 3

Describe the mitochondrial intermembrane space

Answer 3

-contains enzymes that use ATP to phosphorylate other nucleotides
-H+ pumped into this space to create proton grad to drive oxidative phosphorylation - impermeable to H+

Question 4

Describe the inner membrane of mitochondria

Answer 4

-folded into cristae to maximise SA
-contains redox performing proteins of electron transport chain
-proteins for ATP synthesis
-transport proteins to move molecules in + out of matrix

Question 5

Describe the mitochondrial matrix

Answer 5

-internal space containing enzymes of Krebs cycle
-contains: mitochondrial DNA, ribosomes, tRNAs, enzymes, metabolites

Question 6

Do mitochondria contain their own genetic material?

Answer 6

-yes
-circular, double stranded chromosome
-DNA inherited from the mother