adaptive immunity part 1

Question 1

what do antigen presenting cells do in adaptive immunity

Answer 1

• capture microbe
• process it (chop it up into small pieces)
• send signal to T cell and instruct T cell to generate right immune response

Question 2

what is a naïve T cell

Answer 2

T cells that have not previously encountered the antigen

Question 3

what are the different types of antigen-presenting cells, where do they present the pathogen to and what are their functions

Answer 3

dendritic cells- present pathogen to naïve T cells- T cell response against most pathogens
langerhans cells -present pathogen to naïve T cells- T cell response against most pathogens
macrophages- present pathogen to effector T cells - phagocytic activities
B cells - present pathogen to effector T cells- antibody response

Question 4

what are the features of antigen presenting cells

Answer 4

strategic location- mucosal membranes, skin , blood, lymph nodes, spleen
diversity in pathogen capture mechanisms- phagocytosis , macropinocytosis
diversity in pathogen sensors (PRRs)- can detect extracellular and intracellular pathogens