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Imse -1 > Adaptive Immunity -3 > Flashcards

Adaptive Immunity -3 Flashcards

1
Q

B cell progenitors’: contact with bone morrow

A

Pro B cells

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2
Q

Il-7 necessary at this early developmental stage.

A

Pro B cells

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3
Q

Rearrangement of genes

A

Pro B cells

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4
Q

Markers that include surface antigens

A

CD19
CD45
CD43
CD24
C-kit
Tdt
Rag -1
Rag -2

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5
Q

Chromosome involve in rearrangement of genes

A

Chromosome 14

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6
Q

Cd that is always present in every phase

A

CD19

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7
Q

1st heavy chain synthesized al the new chains
Igm- immunoglobulin

A

Pre B sells

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8
Q

2 heavy chains and surrogate light chain

A

Pre B cell

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9
Q

Elimination of B cells that become self reactive receptors

A

Immature B cells

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10
Q

Major histo compatibility complex MHC

class ii molecules

A

CD21, 40

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11
Q

What Cd is important in the interaction of 3 cells within T cells

A

Cd 40

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12
Q

Receptor for breakdown product of component C3.

A

CD21

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13
Q

Remain in the spleen

A

Marginal B cells

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14
Q

Migrate to lymph nodes

A

Follicular B cells

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15
Q

Proteins on the surface of mature B cells

A

Cd 19
cd 21
Cd 81
Cd 225
Cd 19 complex

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16
Q

Presence of CD25 and IL -2

A

Activated B cells

17
Q

Transform into a blast will give rise to both plasma cell and memory cell

A

Activated B cell

18
Q

Antibody production

A

Plasma cells

19
Q

Spherical or ellipsoial cells between 10 and 20 nm

Little no surface immunoglobulin

A

Plasma cells

20
Q

Located in germinal centers in the peripheral lymphoid organ

A

Plasma cells

21
Q

T or F

in bone marrow, plasma cells can curare in niches around by stromal cells

A

True

22
Q

T or F

Plasma cells, found elsewhere are non dwiding and after several days of antibody production they die without proliferation

A

TRUE

23
Q

Responsible for the memory for the adaptive immunity

A

Memory cells

24
Q

Cell to cell contact

A

T-lymphocytes

25
Q

Responsible for cellular immune responses and are involved in the regulation of antibody reactions in conjunction with B lymphocytes

A

T lymphocytes

26
Q

Early surface markers

A

Tells include CD44 and CD25

Imse -1 (14 decks)

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