Acute Medicine Flashcards
1
Q
Superficial epidermal burns
- Initial advice
- When to seek further treatment
- Important prophylaxis if deeper
- Important blood test if smoke inhalation
A
- Cool bath / shower, topical emollients, cold compress, simple analgesics
- Blister formation - may indicate further dermal injury
- Tetanus
- Carboxyhaemaglobin
2
Q
Cardiac arrest
- Rhythm disturbances classed as cardiac arrest
- Bedside tests
- Shockable rhythms
- Adrenaline - method and frequency
- Ant-arrhythmic to consider
- Frequency to check rhythm
- ROSC management
- Reversible causes of CA - 4Hs and 4 Ts
A
- VF, pulseless VT, PEA, asystole
- ABG (pH, lactate, electrolytes), lactate, troponin, glucose
- Pulseless VT, VF
- IV every 3-5 minutes after 3 shocks, or 2mg diluted through ET tube
- Amiodarone
- Every 2 minutes
- ABCDE, SpO2 94-98%, 12 lead ECG, treat precipitating cause
- H (hypothermia, hypovolaemia, hypoxia, hypo/hyperkalaemia), T(thrombus, tamponade, tension, toxins)
3
Q
Hypoglycaemic episode
- 1st line
- 2nd line
- Causes
A
- Oral glucose - if alert (tablets if can swallow)
- IV glucose 20% in saline (if IV access and drowsy), IM glucagon - no IV access
- Insulin, alcohol, liver disease, Addison’s
4
Q
Meningitis
- Differential diagnoses (3)
- Kernig’s sign - what it is, + other cause
- 1st line investigations (bloods, other, imaging)
- Investigation to avoid if septicaemic
- Antibiotics < 3 months for meningitis
- Antibiotics > 3 months-50 years for meningitis
- Add what if recent travel / prolonged or multiple ABX exposure
- Antibiotics for meningococcal disease
- Listeria antibiotics
- Drug to avoid neurological sequelae
- Bacterial LP (white cell, glucose, protein)
- Viral LP (white cell, glucose, protein)
- TB LP (appearance, white cell, glucose, protein)
A
- Encephalitis, septicaemia, SAH
- Pain on passive knee extension when hip is flexed, SAH
- Culture, FBC, CRP, U+E, Ca2+, Mg2+, glucose, coagulation profile, CT head, LP
- LP
- IV cefotaxime + amoxicillin/ampicillin
- IV ceftriaxone
- IV vancomycin
- Ampicillin
- IV amoxicillin + gentamicin
- Dexamethasone
- Polymorph, glucose <1/2 plasma, protein level >1.5
- Mononuclear (lymphocytes), glucose >1/2 plasma, protein level <1
- Fibrin web, mononuclear (lymphocytes) glucose <1/2 plasma, protein level >1.5
5
Q
Encephalitis
- When to suspect
- Investigations
- LP results
- Common organism
- Common area of brain affected + subsequent signs
- CT changes seen
- Management
A
- Abnormal behaviour, reduced consciousness, focal neurological signs PRECEEDED BY INFECTIOUS ILLNESS
- Urine dip, culture, CT, LP (send for PCR)
- Lymphocytosis, elevated protein
- HSV 1
- Temporal lobe, so e.g. aphasia
- Medial temporal and inferior frontal changes (e.g. petechial haemorrhages) (normal in 30%)
- IV aciclovir
6
Q
Poisoning
- Bloods
- Monitoring
Paracetamol overdose
- 1st line if presenting <1 hours post-OD
- When should blood paracetamol level be taken
- Treatment if levels above the treatment line and stable and OD <12 hours ago
- Day after OD, bloods
- Treatment if unsure when OD happened/staggered dose
- NAC - side effects
A
- VBG, LFT, INR, U+E, glucose, FBC, paracetamol/salicyclate levels, toxicology screen
- Vitals, ECG, urine output
- Activated charcoal
- 4 hours post-ingestion
- N-acetylcysteine - IV with dextrose after level
- INR, U+E, LFTs
- Give n-acetylcysteine without waiting for levels
- Hypoglycaemia, bronchospasm, shock, vomiting
7
Q
Maintenance fluids
- Calculation - fluid requirements
- Potassium requirements
- Glucose requirements
- Simple maintenance fluid prescribing
A
- 30ml/kg/24hrs, then work out how many ml per hour
- 1 mmol/kg/day of potassium
- 50-100 g/day of glucose
- 1 saline, 2 dextrose, each with 20mmol of potassium
8
Q
NSTEMI
- Risk stratification tool
A
- GRACE
9
Q
Anaphylaxis
- 12+ adrenaline dose
- 12+ other medications
- 6-12 management
- 0.6-6 management
A
- 1:1000 0.5ml (500 micrograms) IM
- 10mg chlorphenamine, 200mg hydrocortisone, 5mg nebulised salbutamol
- 0.3ml A, 5mg C, 100mg H, 5mg S
- 0.15 A, 2.5mg C, 50mg H, 2.5mg S
10
Q
Head injury
- CT scan (within 1 hour) criteria
- Basal skull fracture signs
Extradural haematoma
- Location
- Cause
- Presentation
Subdural haematoma
- Location
- Presentation
- Risk factors (3)
- Raised ICP - medical management (2)
A
- GCS <3 initially, GCS <15 after 2 hours, suspected open or depressed skull fracture, any sign of basal skull fracture, post-traumatic seizure, 2+ vomiting, focal neurological deficit
- Haemotympanum, ‘panda’ eyes, cerebrospinal fluid leakage from the ear or nose, Battle’s sign
- Arterial bleed between dura and skull
- Temporal bone fracture causing rupture of the middle meningeal artery
- Quicker onset than subdural, raised ICP features, potentially lucid interval
- Venous bleed of outermost meninges layer
- Little while after a fall, become drowsy, slow onset of symptoms
- Old age, alcoholism, anticoagulation
- Mannitol, furosemide
11
Q
GI bleed
- Initial management
- Initial bloods
- Fluid management
- Upper GI immediate investigation
- If variceal bleed identified, give
A
- Protect airway, NBM, 2 large bore cannula, catheterise, observations every 15 mins
- Coagulation, G+S and cross match
- Normal saline fast until blood arrives, consider FFP for low platelets, correct coagulopathy
- OGD
- Broad spectrum antibiotics, terlipressin
12
Q
Status epilepticus
- Bloods
- Bedside tests
- Others to consider
- Initial management
- Further management if no response
- Definitive management
- If first presentation seizure, what is likely
A
- FBC, U+E, LFT, glucose, lactate, VBG, CRP, Ca2+
- Urine dip/culture, observations, ECG
- Toxicology screen, CT, EEG
- ABCDE, lorazepam (2-4mg slow IV bolus, can give another dose in 10 minutes) or diazepam (rectal)
- Phenytoin (IV infusion), thiamine (if ? alcohol), 50ml of 20% glucose (if hypo), treat acidosis/hypotension
- General anaesthetic
- Structural brain abnormality >50%
13
Q
Shock
- Definition
- Mean arterial pressure - calculation
- Cardiac output - calculation
- Inadequate CO - causes (2 broad)
- SVR loss - cause (4)
A
- Circulatory failure resulting in inadequate organ perfusion
- Cardiac output (CO) x Systemic vascular resistance (SVR)
- Heart rate x Stroke volume
- Hypovolaemia (bleeding / fluid loss), pump failure - (arrhythmia, ACS, valve failure)
- Sepsis, anaphylaxis, neurogenic, endocrine (e.g. Addison’s)
14
Q
Drugs
Ecstasy
- Presentation
- Temperature management if supportive fails
Cocaine
- Mechanism
- Cardiovascular effects
- ECG changes
- Neurological effects
- Systemic effects
- If abdominal pain, consider
- 1st line if toxic levels
A
- Agitation, anxiety, confusion and ataxia, tachycardia, HTN, low Na+, hyperthermia, rhabdomyolysis
- Dantrolene
- Blocks uptake of dopamine, noradrenaline and serotonin
- MI, abnormal HR, HTN, aortic dissection
- Ischaemic changes, wide QRS, prolonged QT
- Seizures, mydriasis, hypertonia, hyperreflexia
- Hyperthermia, metabolic acidosis, rhabdomyolysis
- Ischaemic colitis
- Benzodiazipines
15
Q
Opioid overdose
- Presentation
- 1st line management
- Complications
A
- Pinpoint pupils, drowsiness, rhinorrhoea, watering eyes, yawning, track marks, respiratory depression
- Naloxone 400 micrograms IV
- Viral infection, infective endocarditis, VTE