Acute Leukemias

Question 1

Favorable risk cytogenetics in ALL

Answer 1

Hyperdiploidy
t(12;21)

Question 2

Acute leukemia-like disease, CD123+, CD4+, CD56+

Answer 2

Blastic Plasmacytoid Dendric Cell Neoplasm

Question 3

Favorable cytogenetics for AML.

Answer 3

t(8;21), inversion (16), mutated NPM1 without FLT3 mutation or with low FLT3-ITD, biallelic mutated CEBPA.
Don’t need transplant, can just induce and consolidate.