Acute Leukemia

Question 1

What is acute leukemia?

Answer 1

A malignancy of the hematopoietic progenitor cell

Question 2

What is the most common leukemia in childhoods?

Answer 2

ALL

Question 3

What are the signs of acute leukemia?

Answer 3

Fatigue, fever, and bleeding

Question 4

What do the lab tests of AML reveal?

Answer 4

a CBC reveals increased WBC count with blasts (blasts being characteristic)

Question 5

What’s the supportive treatment of AML?

Answer 5

Sperm cryoperservation, substitution of red cells, suppression of menstruation

Question 6

The induction therapy for AML uses a 7’3 rule, what’s that?

Answer 6

7 day IV cytarabine at 100mg, and 3 days bolus IV anthracycline

Question 7

Clinical features of ALL?

Answer 7

Lymphadenopathy, spleno and hepatomegaly

Question 8

Which clinical feature is exclusive to ALL?

Answer 8

Bone pain

Question 9

Under a light microscope, we don’t see Auer rods, why?

Answer 9

They are exclusive to the myeloid leukemia