Acute Hepatitis Flashcards
Acute inflammation of the ….. is what states acute hepatitis
Liver parenchyma
what is the time cutoff between acute and chronic hepatitis
6 months
In Primary Biliary Cholangitis, what occurs (process)?
AI destruction of the biliary ducts
What is the most common cause of acute hepatitis (not type)
Infectious
Which type of hepatitis virus is more common in the uK
Hep C most Common
How is HAV transmitted?
What area does it affect of the liver?
F=O Via Shellfish
Zone 3 hepatic lobule
Incubation time for HAV?
How do you test for it?
2-3 weeks
Anti-HAV IgM serum
What are the 2 treatments for HAV?
Conservative => Vaccine
Do nothing ==> Its self resolving
What is the name of the HAV?
RNA Picornavirus
the E-antigen is indicative of what virus?
HBV
How is HBV transmitted (3)
Sex // Needles // Infected blood products
What is the incubation time for HBV?
1-5months
How do you test if a PX has HBV?
HBV DNA Serum ==> HBsAg
What are 2 anti-viral drugs excluding IF which is used in HBV
Tenofovir + Adefovir
What is the name of the IF drug used in HBV
Pegylated alpha 2a IF
What are 2 complications of HBV OR HDV exposure (liver)
Hepatocellular Carcinoma
Hepatic Cirrhosis
What is the name of HCV?
RNA Flavivirus
How can HCV be transmitted occasionally?
Vertically
**mainly needles // Blood products
incubation time of HCV?
6-9wks
What drug can you give for HCV?
Pegylated alpha 2a IF
Symptoms of HCV?
Can remain asymptomatic for years and not know about it
What virus co-infects with HBV?
HDV
What is the incubation time for HDV?
1-5months
Drug used in HDV?
Pegylated Alpha 2a IF
HEV is what type of virus?
RNA
How is HEV transmitted?
F=O + Contaminated water
Incubation time for HEV
2-3 weeks
What test do you do for HEV? (2)
IgM + IgG anti HEV
What is the main treatment for HEV?
Self-limiting
What group of women are at high risk of mortality with HEV?
Pregnant women (20%)