Acute Hepatitis Flashcards

1
Q

Acute inflammation of the ….. is what states acute hepatitis

A

Liver parenchyma

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2
Q

what is the time cutoff between acute and chronic hepatitis

A

6 months

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3
Q

In Primary Biliary Cholangitis, what occurs (process)?

A

AI destruction of the biliary ducts

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4
Q

What is the most common cause of acute hepatitis (not type)

A

Infectious

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5
Q

Which type of hepatitis virus is more common in the uK

A

Hep C most Common

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6
Q

How is HAV transmitted?

What area does it affect of the liver?

A

F=O Via Shellfish

Zone 3 hepatic lobule

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7
Q

Incubation time for HAV?

How do you test for it?

A

2-3 weeks

Anti-HAV IgM serum

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8
Q

What are the 2 treatments for HAV?

A

Conservative => Vaccine

Do nothing ==> Its self resolving

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9
Q

What is the name of the HAV?

A

RNA Picornavirus

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10
Q

the E-antigen is indicative of what virus?

A

HBV

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11
Q

How is HBV transmitted (3)

A

Sex // Needles // Infected blood products

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12
Q

What is the incubation time for HBV?

A

1-5months

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13
Q

How do you test if a PX has HBV?

A

HBV DNA Serum ==> HBsAg

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14
Q

What are 2 anti-viral drugs excluding IF which is used in HBV

A

Tenofovir + Adefovir

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15
Q

What is the name of the IF drug used in HBV

A

Pegylated alpha 2a IF

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16
Q

What are 2 complications of HBV OR HDV exposure (liver)

A

Hepatocellular Carcinoma

Hepatic Cirrhosis

17
Q

What is the name of HCV?

A

RNA Flavivirus

18
Q

How can HCV be transmitted occasionally?

A

Vertically

**mainly needles // Blood products

19
Q

incubation time of HCV?

A

6-9wks

20
Q

What drug can you give for HCV?

A

Pegylated alpha 2a IF

21
Q

Symptoms of HCV?

A

Can remain asymptomatic for years and not know about it

22
Q

What virus co-infects with HBV?

A

HDV

23
Q

What is the incubation time for HDV?

A

1-5months

24
Q

Drug used in HDV?

A

Pegylated Alpha 2a IF

25
Q

HEV is what type of virus?

A

RNA

26
Q

How is HEV transmitted?

A

F=O + Contaminated water

27
Q

Incubation time for HEV

A

2-3 weeks

28
Q

What test do you do for HEV? (2)

A

IgM + IgG anti HEV

29
Q

What is the main treatment for HEV?

A

Self-limiting

30
Q

What group of women are at high risk of mortality with HEV?

A

Pregnant women (20%)