Acute Care and Trauma Flashcards

1
Q

Define ARDS

A

A syndrome of acute and persistent lung inflammation with increased vascular permeability

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2
Q

What is a pulmonary infiltrate?

A

A substance, thicker than air (eg pus/blood) lingering in the parenchyma.

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3
Q

Recall the characteristics of ARDS

A

A - Absence of raised capillary wedge pressure
R - Reduced blood oxygen (hypoxaemia)
D - Double-sided infiltrates (bilateral infiltrates)
S - sudden onset (acute)

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4
Q

Explain the aetiology of ARDS

A

Severe insult to lungs
Inflammatory mediators released
Capillary permeability increases
Results in pulmonary oedema, reduced gas exchange and reduced lung compliance.
(Injury, inflammation, increased permeability)

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5
Q

Recall some causes of ARDS

A
TOAST crumbs and apple PIPs can make you choke - 
Transfusion
Overdose of drugs
Aspiration
Sepsis
Transplantation

Pneumonia
Injury/burns
Pancreatitis

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6
Q

Recall the pathological stages of ARDS

A

Exudative
Proliferative
Fibrotic

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7
Q

Recall the signs of ARDS

A
Think SMURF: fast, blue, noisy:
Cyanosis 
Tachypnoea
Tachycardia
Widespread crepitations
Hypoxia refractory to oxygen treatment 
(Usually bilateral)
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8
Q

Identify appropriate investigations for ARDS

A

Bloods
Imaging = CXR to look for bilateral infiltrates
ECG - to look for mitral valve dysfunction (=valve beneath LA: dysfx –> build up of pressure in lungs)
PAC to check PCWP (pressure in left atrium)

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9
Q

Recall the presenting symptoms of ARDS

A
Cough Sometimes Decreases Respiratory Function - 
Cough
Symptoms of cause
Dyspnoea
Respiratory distress
Functional deterioration
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10
Q

Why does alcohol withdrawal cause symptoms?

A

Body has increased sensitivity to glutamate in alcoholics so when alcohol consumption stops there are excitatory symptoms

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11
Q

Recall the presenting symptoms of alcohol withdrawal

A

HAD A PINT
Headache
Anxiety
Depression

Anorexia

Palpitations
Insomnia
Nausea
Tremor

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12
Q

What is the acute confusional state caused by alcohol withdrawal called?

A

Delirium tremens

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13
Q

Recall the features of delirium tremens

A

Sweating
Hallucinations
Tremor

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14
Q

What is the management plan for alcohol withdrawal

A
*ABCDE*
Amobarbital
B1 vitamin (thiamine)
Chloro-
Diaz-
Epoxide
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15
Q

What is the reason for fatality in alcohol withdrawal?

A

Seizures (generalised tonic-clonic)

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16
Q

Distinguish immunogenic and non-immunogenic anaphylactic shock

A

Immunogenic involves IgE and immune complexes, non-immunogenic = mast cell/basophil degranulation without Ig involvement

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17
Q

Recall some symptoms of anaphylaxis

A

Symptoms of anaphylaxis will make the patient SOB:
Skin (rash, pruritis)
Oedema (lips, face)
Breathing (short, wheezing)

18
Q

Recall the signs of anaphylaxis

A
URTICARIA:
Urticaria
Reduced BP
Tachypnoea
Infected conjunctiva
Cyanosis
Audible wheeze
Rhinitis
Increased heart rate
Airway swelling
19
Q

Recall an appropriate management plan for anaphylaxis

A
Oxygen Can Help Anaphylaxis:
Oxygen
Chloropheniramine
Hydrocortisone
Adrenaline (IM)
20
Q

Recall the pathophysiology of aspirin overdose

A
Really High Aspirin Consumption Does Harm Always
Resp centre stimulation
Hyperventilation
Alkalosis (respiratory)
Compensation by kidneys: urine bicarb and K+ increased
Dehydration
Hypokalaemia
Acidosis (metabolic)
21
Q

Recall the presenting symptoms of aspirin overdose

A
OVERDOSE
Over-
Ventillation
Ears ringing
Red-faced
Dizziness
Overtired
Sweating
Epileptic-looking
22
Q

Recall the signs of aspirin OD on physical examination

A

Fever
Tachycardia
Hyperventillation
Epigastric tenderness

23
Q

Recall the appropriate investigations for aspirin OD

A

Bloods (including salicylate and ABG to show acidosis/alkalosis)
ECG (to look for hypokalaemia)

24
Q

Recall the 3 severities of burns injury and the approx healing time for each of these

A

Superficial - 7 days
Deep - 21 days
Full thickness - requires skin graft

25
What is it important to check for in burns injury that you might forget?
Inhalational njury
26
What investigations should be done in an electrical burn case?
CK ECG Urine myoglobin
27
Which is the most commonly injured artery in extradural haemorrhage?
Middle meningeal artery
28
Recall the characteristic progression of extradural haemorrhage
Temporary loss of consciousness --> lucid phase --> deterioration of GCS
29
Recall the signs of extradural haemorrhage
``` Mnemonic: Sudden damage can result in haemorrhage Scalp trauma Deteriorating GCS Raised ICP Headache ```
30
What is indicative of extradural haemorrhage on CT?
Shift in midline that shows raised ICP
31
Define multi-organ dysfunction syndrome
Affects 2 or more organ systems and is induced by variety of insults including *sepsis*
32
How is MODS measured?
It is scored 1-4
33
Summarise the 4 MODS scores
1: Mild respiratory alkalosis and hyperglycaemia 2: Hypoxia + tachypnoea, liver dysfunction 3: Acid-base disturbance, azotaemia, coagulation abnormalities (due to liver dysfunction) 4: Lactic acidosis, ischaemic colitis, vasopressor dependent
34
What is the main investigation in MODS
ABG - need to asses where they are in the alkalosis --> acidosis spectrum
35
Recall the symptoms of opiate overdose
``` Mnemonic: Codeine Never Softens Anyone's Crap Constipation Nausea Sedation Anorexia Cravings ```
36
Recall the signs of opiate overdose
Pinpoint pupils Tachycardia with hypotension Respiratory depression
37
What drug is used to combat opiate overdose?
Naloxone
38
What is the result of paracetamol overdose?
Hepatic necrosis
39
After how many hours does paracetamol overdose begin to really show symptoms
24 hours
40
What are the symptoms of paracetamol OD?
RUQ pain and jaundice, develops into jaundice and encephalopathy
41
Recall the necessary investigations in paracetamol OD (think about liver fx)
``` FBC U&E, LFT Clotting Glucose ABG Salicylate ```