ACT8 CRP Flashcards
Non specific consti. of serum
CRP
CRP is an abnormal ___ w/c appears in the SERA of indv in response to ____ and ____ and disappears when _ subsides
inflammatory conditions
tissue necrosis
Found in
bacterial infxn viral infxn active RF active RA TB malignant dse
CRP is Ig_ in nature
IgG
CRP is an acute phase reactant produced by the __ under the control of _
liver
Il-6
is a direct and quantitative measure of the APR
CRP
appears earlier than an elevated _
ESR
APR (other plasma prot|)
CRP Haptoglobin Alpha 1 Antitryp Fibrinogen Cerulopla Alpha 2 macroglobin Transferrin
Serologic dx
CRP LAT Fluorescent Ab Pption Electrophoresis/electroimmunodiffusion Radioimmunoassay
Clinical Significance
Screening for inflammatory and malignant organic dse
Monitoring therapy in inflammatory dse
Clinical Significance ELEVATED IN
Septicemia
Meningitis in neonates
Burns
MI etc
ESR can be affected by factors unrelated to inflamm such as
Anemia
Fibrinogen Albumin levels