Act 10 RA Flashcards
1
Q
chronic systemic dse characterized mainly by recurrent inflammatory episodes involving the synovium
A
rheumatoid arthritis
2
Q
The main immunologic finding in RA is the presence of
A
RF
3
Q
most often the Ig_ class is directed against the _ portion of the Ig_
A
M, Fc, G
4
Q
M with G deposit in JOINTS resulting in
A
type 2 hypersensitivity rxns
5
Q
Serologic dx
A
Rapid LAT
Rose-Waaler Test
Plotz-Singer LT
6
Q
Rose-Waaler test AKA
Indicators: Reactants
A
Sensitized sheep cell agg test
Indicators: Reactants
Sheep RBC - rabbit anti-sheep hemolysin
Tanned Sheep RBC - human fraction II gamma globulin
Bentonite particles - human fraction II gamma globulin
7
Q
Clinical significance
A
RA
Felty’s syndrome
Juvenile RA
Still’s dse
8
Q
Biologic false positives
A
SLE Sjogren's synd Syphilis Hepa RF TB