Act 10 RA Flashcards

1
Q

chronic systemic dse characterized mainly by recurrent inflammatory episodes involving the synovium

A

rheumatoid arthritis

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2
Q

The main immunologic finding in RA is the presence of

A

RF

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3
Q

most often the Ig_ class is directed against the _ portion of the Ig_

A

M, Fc, G

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4
Q

M with G deposit in JOINTS resulting in

A

type 2 hypersensitivity rxns

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5
Q

Serologic dx

A

Rapid LAT
Rose-Waaler Test
Plotz-Singer LT

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6
Q

Rose-Waaler test AKA

Indicators: Reactants

A

Sensitized sheep cell agg test

Indicators: Reactants
Sheep RBC - rabbit anti-sheep hemolysin
Tanned Sheep RBC - human fraction II gamma globulin
Bentonite particles - human fraction II gamma globulin

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7
Q

Clinical significance

A

RA
Felty’s syndrome
Juvenile RA
Still’s dse

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8
Q

Biologic false positives

A
SLE
Sjogren's synd
Syphilis
Hepa
RF
TB
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