Acromegaly Flashcards
1
Q
Where is GH produced?
A
Ant pit
2
Q
What do tumours of ant pit cause?
A
Bitemporal hemianopia
3
Q
What are clinical features of acromegaly?
A
Acral enlargement Arthalgia Large tongue Frontal bossing Excessive sweating Skin tags Headache Hypogonodal symptoms HTN Heart disease Sleep apnoea T2DM
4
Q
How is acromegaly diagnosed?
A
IGF-1 screening and MRI
GH fluctuates too much!
5
Q
How is Acromegaly managed?
A
Pituitary surgery
OCREOTIDE (blocks Gh release)
BROMOCRIPTINE or Cabergoline (dopamine agonists)
6
Q
What else do ant pit tumours cause/
A
Prolactinaemia Cushings Craniopharyngioma Hypopituitarism Bitemporal hemianopia