Acromegaly Flashcards

1
Q

Where is GH produced?

A

Ant pit

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2
Q

What do tumours of ant pit cause?

A

Bitemporal hemianopia

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3
Q

What are clinical features of acromegaly?

A
Acral enlargement
Arthalgia
Large tongue
Frontal bossing
Excessive sweating
Skin tags
Headache
Hypogonodal symptoms
HTN
Heart disease
Sleep apnoea
T2DM
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4
Q

How is acromegaly diagnosed?

A

IGF-1 screening and MRI

GH fluctuates too much!

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5
Q

How is Acromegaly managed?

A

Pituitary surgery
OCREOTIDE (blocks Gh release)
BROMOCRIPTINE or Cabergoline (dopamine agonists)

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6
Q

What else do ant pit tumours cause/

A
Prolactinaemia
Cushings
Craniopharyngioma
Hypopituitarism
Bitemporal hemianopia
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