Acquired Disorders of Cloatting

Question 1

• Deficiency prevents activation of clotting factors, and hypocoagulation.
• Result of poor dietary intake; malabsorption, decreased production by enteric bacteria

Answer 1

Vitamin K deficiency

Question 2

Uncontrolled local or systemic clotting leads to decrease in clotting factors, fibrinogen and thrombocytopenia

Answer 2

Disseminated Intravascular Coagulation (DIC)

Question 3

Impaired liver function results in decrease in synthesis of clotting factors

Answer 3

Coagulopathy of liver Disease

Question 4

-Destruction of marrow or failure of hematopoiesis due to suppression or injury to hematopoietic cells
-Causes range from idiopathic to expires to toxin/drugs/radiation
Dx: General pancytopenia

Answer 4

Aplastic anemia