ACLAM Position Statements Flashcards
Does ACLAM support the adoption of animals post-study?
Yes, of healthy, post-study research animals into long term private homes or farms
Can an adoption program include collaboration with outside placement groups?
Only after careful review of the group’s mission statement, reputation, history of involvement with animal adoption, and criminal background.
Does ACLAM support post-adoption transfer?
No, permanent homes
Do major surgical procedures and prior administration of experimental compounds preclude animals being adopted?
No, the decision should be made based on the animal’s current health status and long-term prognosis, in addition to potential safety concerns for adopters.
Are genetically modified animals excluded from adoption?
Not necessarily, but applicable guidelines must be reviewed and followed to ensure compliance with regulatory guidelines.
Define results reproducibility.
Ability of a researcher to independently duplicate to the greatest extent possible the results of a prior study using the same materials and methods as the original investigator. Similar to the definition of replicability.
Define methods reproducibility.
Indicates that sufficient details regarding methods and materials have been provided such that other researchers have the appropriate information needed to reproduce a study.
Define inferential reproducibility.
Researcher comes to similar conclusions or derives knowledge of similar impact from an independent study or re-analysis of the original study.
Define repeatability.
When the same researcher repeats an experiment using the same equipment and obtains similar results.
What are intrinsic and extrinsic animal factors?
Intrinsic - Animal genetics, sex, age, and microbiome
Extrinsic - Direct impact on the experience of the animal, such as housing, husbandry, handling, feed, enrichment, caging type, therapeutic intervention, light cycle
Do rodents require individual health records?
No. If needed, group records may be acceptable.
What animals require individual medical records?
Animals that receive regular individual health evaluations, as deemed appropriate by the institution and regulations.
Do clinical notations related to a disease that is experimentally induced in animals need to be maintained in a medical record?
No, may be in research records, but the info must be readily available for review by vet staff and internal and external oversight.
What are the components of a medical record? (10)
- Identification
- Clinical information
- Immunization and prophylactic treatment
- Diagnostic tests and interpretation
- Reference to research intervention
- Treatment provided, response, and follow-up
- Surgery, anesthesia, analgesia, and post-op care
- Control of pain and distress
- Documentation of euthanasia or other disposition
- Necropsy findings
Who should make notations in the medical record?
Individuals who have administered treatments or made direct observations or evaluations of the animals or their diagnostic results, or their designee
What information should be included with all medical record entries?
Dated, indicate the originator of the entry, and be legible to someone other than the writer.
How can routine preventative medical procedures on an entire group of animals be recorded?
As a group record.
What should surgical records include? (8)
- Identification and date
- All drugs administered, including dosage, route, time, and ability to identify person administering
- Description of procedure and ID or surgeons
- Ongoing findings during monitoring
- Notation of any variations from normal during procedure, including actions taken and time performed, animal’s response, and ability to identify person taking actions
- Assessment for pain and distress
- Actions taken to alleviate pain and distress and response
- Notation defining end of monitoring period, including time, date, and ability to identify
How often must consulting veterinarians make regularly scheduled visits?
As needed, with further arrangements to ensure that veterinary services are readily available at all other times.
Who is responsible for ensuring that only facilities with programs appropriate for the intended surgical procedures are utilized and that personnel are adequately trained?
Institution, delegated to the vet or IACUC.
What should be provided to the institution and investigators regarding drug selection?
Recommendations regarding the selection and use of anesthetics, analgesics, sedatives, pain assessment, and euthanasia practices for all species.
