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Vitamine > Acid Folic > Flashcards

Acid Folic Flashcards

1
Q

DENUMIRE ACID FOLIC

A

acid pteroil glutamic

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2
Q

ALCATUIRE ACID FOLIC

A

pteridina acid para amino benzoic
acid pteroic acid glutamic
acid pteroil glutamic

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3
Q

SURSE BIOLOGICE AF

A

acid pteroic 3,5,7 poligutamic la COOH gama-absorbit cu hidroliza in prez hidrolazei- acid folic - perete intestinal +CH3 in prez B12-hidrogenare- THF si B12-CH3

sinteza de ADN si celule noi

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4
Q

ROLUL AF CA TRANSPORTOR

A

transporta CH2-OH, CH=O, CH=NH, CH3

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5
Q

ROLURI THF

A

homocisteina-metionina
serina-gli
B12 activ
Uracil-timina

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6
Q

DEFICIT AF

A

intrauterin blocheaza capacitatea tubului neural spina bifida si anencefalia
-> reducerea sint ADN, anemie macrocitara , reticulocitoza
U-TS-T deci in deficiente se blocheaza diviziunea celulara iar nucl capata aspectul anormal deci scade sint ADN si creste ARN
anemia macrocitara apar celule megaloblastice scade sint ADN si creste ARN 0.85 raportul
creste conc homocisteinei deci apar boli cardiovasculare

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