Acid-Base Disorders Podcast

Question 1

Increased AGAP

Answer 1

Glycols 
5-oxoproline (chornic acetaminophen)
L-lactate (acidosis in iron isonizazid/shock)
D-lactate
Methanol
Aspirin
Renal Fialure
Ketoacidosis

Question 2

Met acidosis with normal AGAP

Answer 2

Diarrrhea or RTA

Question 3

Delta ratios

Answer 3

MeasuredAGAP-normal AGAP/Normal HCO3-measured HCO3

Less than 1 - high AGAP acidosis with concurrent normal AGAP acidosis

1-2 - pure high AGAP acidosis (lactic acdosis or DKA)

> 2 - High AGAP acidosis with concurrent metabolic alkalosis

Question 4

Albumin effect on Normal AGAP

Answer 4

For every 1 below 4, decreases normal AGAP by 2.5

Question 5

Metabolic alkalosis

Answer 5

Vomting/diuretics

Initial mechanil ventilation of chronicnall hypercarbic patients

MC excss states

Question 6

Resp alkalsosi

Answer 6

Early hypoxemic resp failure

Primary hyperventilation

Progestin states

Question 7

Resp acidosis

Answer 7

Disorders of respiratory apparatus

Drugs or damage to the brainstem