Acid-Base Balance Flashcards
What factors affect alveolar ventilation
Neuromuscular chain defects
Pulmonary disease: airway obstruction, alveolar filling, atelectasis, perfusion blockage, loss of lung parenchyma
what is body pH
7.4
What do the kidneys produce to maintain balance
bicarbonate
What is respiratory acidosis/alkalosis caused by
PCO2
HCO3 = normal
What is metabolic acidosis/alkalosis caused by
HCO3
PCO2 = normal
Characteristics of resp acidosis
PCO2 high
HCO3 normal
Characteristics of resp alkalosis
PCO2 very low
HCO3 normal
Characteristics of metabolic acidosis
HCO3 low
PCO2 normal
Characteristics of metabolic alkalosis
HCO3 high
PCO2 normal
another word for respiratory acidosis
hypercapnia acidosis
What is respiratory acidosis caused by
alveolar hypoventilation
acute airway obstruction with under ventilation
what causes respiratory acidosis
late acute asthma acute COPD Opiate overdose stroke neuropathy myopathy
what are the conditions of compensated respiratory acidosis
HCO3 high
PCO2 very high
pH low
what are the condition of uncompensated respiratory acidosis
HCO3 normal
PCO2 high
pH very low
another name for respiratory alkalosis
hypocapnic alkalosis
respiratory alkalosis is alveolar hypoventiltion/hyperventilation due to …
hyperventilation
early acute asthma with over venitlation
causes of respiratory alkalosis
pulmonary embolus, pneumonia, pulmonary oedema
anxiety
compensated respiratory alkalosis: PCO2 is low/high, HCO3 is low/high/normal, pH is low/high/normal
pCO2 low
HCO3 low
pH normal (slightly high)
compensated respiratory alkalosis: PCO2 is low/high, HCO3 low/high/normal, pH is low/high/normal
PCO2 very low
HCO3 normal
pH very high
another name for metabolic acidosis
hypobicarbonatemic acidosis
what is metabolic acidosis characterised by
excess H ions (low HCO3)
causes of metabolic acidosis
Diabetic ketoacidosis
Acute renal failure
Circulatory Shock - Septic, Cardiogenic, Hypovolemic
Metabolic acidosis with respiratory compensation HCO3 is low/high, PCO2 low/high/normal and pH is low/high/normal
HCO3 = low PCO2 = lower than normal pH = normal (slightly low)
uncompensated Metabolic acidosis: HCO3 is low/high, PCO2 low/high/normal and pH is low/high/normal
HCO3 = very low PCO2 = normal pH = very low
another name for metabolic alkalosis
hyperbicarbonatemic alkalosis
what is metabolic alkalosis characterised by
excess HCO3 ions
what is metabolic alkalosis caused by
Loss of gastric fluid: vomiting
Diuretics- K+ loss: excess renal HCO3 reabsorption
Post hypercapnic mechanical ventilation
compensated metabolic alkalosis: HCO3 is low/high/normal, PCO2 is low/high/normal and pH is low/high/normal
HCO3 = high PCO2 = high pH = normal (slightly high)
uncompensated metabolic alkalosis: HCO3 is low/high/normal, PCO2 is low/high/normal and pH is low/high/normal
HCO3 = very high PCO2 = normal pH = high
what varies in respiratory acidosis/alkalosis
PCO2
what varies in metabolic acidosis/alkalosis
HCO3
pH < 7.4 suggests
acidosis
PCO2 > 40 mmHg suggests
respiratory acidosis
HCO3 < 24 mmol/l suggests
metabolic acidosis
pH > 7.4 suggests
alkalosis
PCO2 < 40 mmHg suggests
respiratory alkalosis
HCO3 > 24 mmol/l suggests
metabolic alkalosis
Characteristics of type 1 respiratory failure
decreased PaO2
decreased PaCO2
alveolar hyperventilation
characteristics of type 2 respiratory failure
decreased PaO2
increased PaCO2
alveolar hypoventilation