Acid Base Balance Flashcards
Why do we need to monitor Acid Base Balance?
-Measure Respiratory Function
-Make changes in treatment
ACID
Donate hydrogen ions when dissolved in water
(More Hydrogen ions = Stronger Acid)
ALKALINE
Accepts hydrogen ions when dissolved in water
(Break apart to from negatively charged ions, hydroxide)
BUFFER
Any substance that can bind or release Hydrogen ions (capable of donation/acceptable)
HCO-3 system
Phospate and Ammonia Buffer System
Protein Buffer System
What is the Carbonic Acid-Bicarbonate Buffer System Equation?
CO2 + H2O ⇌ H2CO3 ⇌ H + HCO3-
Seeks to balance things all the time
What is the Phosphate and Ammonia Buffer System?
Important in buffering ICF and Urine
(happens in the proximal tubule of the kidney)
What is the Protein Buffer System?
Plasma + IC Proteins are the most powerful protein buffers. Haemoglobin is a protein that buffers extra hydrogen molecules
What is the difference between hyper/hypoventilation?
Hyper - Too much volume (<4.6 Alkaline)
Hypo - Under ventilating (>6.9 Acid)
Respiratory Acidosis
Lungs fail to eliminate CO2
Metabolic Acidosis
Excess acid or reduced bicarbonate production
Respiratory Alkalosis
Lungs eliminate too much CO2
Metabolic Alkalosis
Excess Base production