Acid Base Balance Flashcards
PH range
Amount of acid to base in blood (1carbonic acid to 20 base bicarbonate)
7.35-7.45
<7.35=acidosis
>7.45=alkalosis
CO2
When CO2 is elevated think acid
35-45 normal
<35=acidosis
>45=alkalosis
Lungs control CO2
Regulation of CO2
CO2 too high: respirations increase to “blow off” acid
CO2 too low: respirations decrease to hold onto acid
Lungs are quick to fix
HCO3
Main base
22-26 normal
<22=acidosis
> 26=alkalosis
Regulated by kidneys
Regulation of HCO3
HCO3 low: kidneys retain HCO3 or excrete acid
HCO3 high: kidneys excrete HCO3 or retain acid
Kidneys are slower to fix than lungs
(Metabolic parameters)
Oxygenation
Pa02
Normal : 80-100 (95-100% sats)
Mild hypoxemia 60-80 (90-95% sats)
Moderate: 40-60 (75-90%)
Severe <40 (75% sats)
Respiratory acidosis ***
PH <7.35
CO2>45mmHg
Inadequate elimination of CO2 by lungs
Retaining CO2
Respiratory acidosis etiology ***
COPD
Respiratory muscle weakness
Head injury
Drug overdose, over sedation
Pneumothorax
Pneumonia, atelectasis
Respiratory acidosis s/s ***
Restlessness
Coma
Seizures
Dysrhythmias from hyperkalemia
Respiratory alkalosis ***
PH>7.45
CO2<35
Excessive elmination of CO2
“Blowing off CO2”
Respiratory alkalosis causes ***
Hyperventilation due to:
Fear, pain, anxiety, fever
Resp alkalosis s/s ***
Light headedness
Numbness/tingling
Tachycardia
Cardiac dysrhythmias drom hypokalemia
Metabolic acidosis ***
PH<7.35
HCO3 <22
Too much acid
Not enough base
Metabolic acidosis etiology ***
Increased acid:
Renal failure
DKA
Starvation
Hypoxia/shock
Loss of bicarbonate (base):
Diarrhea
Intestinal fistulas
Metabolic acidosis s/s ***
Dysrhythmias r/t hyperkalemia
Kussmaul resp
*deep, rapid RR
Lungs trying to compensate
Metabolic alkalosis ***
PH>7.45
HCO3>26
Too much base
Not enough acid
Metabolic alkalosis etiology ***
Too much base:
Excessive use of bicarbonate
Excess ingestion of antiacids
Loss of acid:
Vomiting
NG suction
Diuretics
Metabolic alkalosis s/s ***
Muscle twitching
Cramping
N/V
Hypoventilation-lungs trying to compensate
Compensation ***
If the ph falls out of range and the body trys to return it to normal
2 systems try to do this:
Lungs and kidneys
If the problem is respiratiory (CO2) what will compensate?
Kidneys (HCO3)
If the problem is metabolic (HCO3) who will try to compensate?
LUNGS (CO2)
Uncompensated ***
PH abnormal plus either CO2 or HCO3 are abnormal
Partial compensation ***
PH, CO2, and HCO3 are all abnormal
Body has started compensating but havnt got PH back to normal
What results will you see if its fully compensated
PH normal with CO2 and HCO3 abnormal
If when compensated the PH is:
7.35-7.39=acidosis
7.411-7.45=alkalosis
ROME abbreviation ***
RO:
Respiratory opposite
PH and CO2 move in opposite directions
ME:
Metabolic equal
PH and HCO3 move in the same direction