Acetyl CoA and ETC part 3 Flashcards
Electron transport
- Uses ELECTRON CARRIERS
- Transfers HYDROGEN IONS and ELECTRONS from NADH and FADH2 until they combine with OXYGEN
- Forms H2O (water)
- Produces ATP energy
In the electron transport system,
- The electron carriers are ATTACHED to the INNER MEMBRANE of mitochondrion
There are 4 PROTEIN COMPLEXES:
Complex I
Complex II
Complex III
Complex IV
Complex I
NADH dehydrogenase
Complex II
Succinate dehydrogenase
Complex III
CoQ-Cytochrome c reductase
Complex IV
Cytochrome c oxidase
Disruption by ______________ causes the inner membrane to form SMALL VESICLES with ATP synthase structures on the EXTERIOR.
Sonication
The interior of the SUBMITOCHONDRIAL particle represents the
Intermembrane space
Electron transport chain is located in the
Inner mitochondrial membrane
Electron transport chain found in INVAGINATIONS called
Cristae
Erythrocytes DO NOT HAVE
Mitochondria
CANNOT USE OXYGEN to generate utilizable energy (Anaerobic)
Erythrocytes
Contain NUMEROUS mitochondria
Cardiac tissue
use oxygen to generate utilizable energy (highly aerobic)
Cardiac tissue
coenzyme products that CAN LEAVE THEIR ENZYME
Mitochondrial NADH
Mitochondrial FADH2
Enzymes that TRANSFER ELECTRONS TO COENZYME Q (Ubiquinone)
- Glycerophosphate dehydrogenase
- Malate dehydrogenase
- Fatty Acyl-coenzyme-A dehydrogenase
From GLYCEROPHOSPHATE SHUTTLE of cytoplasmic NADH
Glycerophosphate dehydrogenase
From MALATE-ASPARTATE SHUTTLE of cytoplasmic NADH
Malate dehydrogenase
from FATTY ACID during BETA-OXIDATION
Fatty acyl-coenzyme-A
ELECTRON TRANSPORT process is like an ELECTRONIC WATERFALL that powers 3 PROTON pump
- FREE ENERGY of the electron becomes LOWER as it passed on (like a hot ball becoming COOLER as it is passed on)
- Amount of energy released is SUFFICIENT to meet the requirements of the proton pump
Electron is transported by electron carriers grouped together as
3 large protein complexes
MULTISUBUNIT PROTEIN complex containing
Complex I (NADH-Q reductase)
Iron-sulfur cluster
Coenzyme-Q
Complex I (NADH-Q reductase)