acetaminophen Flashcards
acetaminophen slows the production of _____ in the central nervous system
slows production of prostaglandins
what type of therapeutic effects does acetaminophen give
analgesic (pain relief) effects
antipyretic ( reduce fever) effects
______ is preferred to NSAIDs for children suspected of having a viral illness such as chickenpox or flu
Acetaminophen
adverse effects are rare at _____ dosages
rare at therapeutic dosages
___ toxicity can be a complication of acetaminophen
acute toxicity
acute toxicity of acetaminophen can result in ___ damage
liver damage
what are the early manifestations of liver damage resulting from acute acetaminophen toxicity
nausea; vomiting; sweating; diarrhea; abdominal discomfort
early manifestations of liver damage resulting from acute acetaminophen toxicity can progress to ______
progress to hepatic failure; coma; and death
overt indications of hepatic injury resulting from acetaminophen use can appear ____ to _____ hours after ingestion
48 to 72 hrs
to prevent risk of acute acetaminophen toxicity ensure the patient’s daily acetaminophen intake does not exceed ____ limits
do not exceed recommended limits
what is the recommended limit of acetaminophen for most patients
4g/day
what is the recommended limit of acetaminophen for undernourished clients
3g/day
what is the recommended limit of acetaminophen for clients who consume more than 3 servings of alcohol daily
2g/day
what is the antidote for acetaminophen toxicity
Acetylcysteine
how is acetylcysteine administered for acetaminophen toxicity
via duodenal tube
why is the antidote for acetaminophen given via a duodenal tube
to prevent emesis and aspiration
clients should take acetaminophen as prescribed and should not ______ recommended daily dosage
do not exceed
parents should follow provider’s advice regarding administration of acetaminophen to _____
children
acetaminophen is a pregnancy risk category B for what uses
oral; rectal use
acetaminophen is a pregnancy risk category C for _____ use
IV use
clients who have a hypersensitivity to a component; severe liver impairment or disease; kidney impairment; chronic alcohol use disorder or malnutrition
should not use ____
acetaminophen
IV form of acetaminophen should be used cautiously in clients who are
breastfeeding
____used concurrently with acetaminophen can increase risk of liver damage
alcohol
acetaminophen slows the metabolism of warfarin leading to increased levels of warfarin. This places the client at risk for
bleeding
because acetaminophen slows the metabolism of warfarin which can place the client at risk for bleeding, a nurse should monitor _____ and ____ levels and adjust dosage of warfarin accordingly
prothrombin time and INR levels
clients should observe indications for bleeding which are
bruising; petechiae (tiny spots(red/purple) of bleeding under the skin; hematuria (blood in urine)
clients taking acetaminophen should be taught how to read ___ labels carefully so that they can determine the amount of medication contained in each dose
medication label
clients should only take ___ product containing acetaminophen at a time
one
acetaminophen administered orally should be taken with
full glass of water; with or without food
if pain or fever lasts for more than ____ days, client should contact provider
lasts for more than 3 days
adults should not take acetaminophen for more than ____ days
no more than 10 days
children should not take acetaminophen for more than _____ days without provider approval
no more than 5 days
how is the effectiveness of acetaminophen evaluated
relief of pain; fever reduction
