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Anaesthesia > Acepromazine > Flashcards

Acepromazine Flashcards

1
Q

Ace use?

A

Sedation and pre-med

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2
Q

Antagonist of?

A

Dopaminergic receptors (D2), Histaminic (H1) receptors, Cholinergic muscarinic receptors

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3
Q

Routes of admin

A

IM, IV, SQ, PO

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4
Q

Onset of action

A

IV - 5-20min
IM - 30-45 min

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5
Q

Duration of action

A

4-6 hours

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6
Q

metabolism & excretion

A

metabolised in liver, excreted via kidneys

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7
Q

Potentiates the effects of …

A

Opioids, Local anaesthetics, general anaesthetics, organophosphate compounds

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8
Q

Sedation is…

A

not as effective as using an alpha 2
*higher dose - longer duration

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9
Q

Handy feature?

A

anti-emetic (handy when given with morphine as morphine can cause vomiting)

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10
Q

Seizures?

A

*may LOWER the seizure threshold in epileptic patients

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11
Q

Cardiovascular effects

A

Hypotension
Anti-arrhythmic

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12
Q

Resp effects?

A

minimal

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13
Q

GIT effects

A

antispasmodic
decreased oesophageal sphincter tone
decreased gastric emptying - *risk of regurgitation

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14
Q

body temp effects?

A

hypothermia due to vasodilation

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15
Q

Reversal?

A

no - administer an alpha 1 agonist to counteract vasodilation (phenylephrine, methoxamine), IV fluids
adrenaline CONTRA due to vasodilatory effects

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16
Q

Avoid when…

A

hypovolaemia, sick animals

17
Q

Use with care in…

A

Giant breeds - reduce dose
Boxers - vasovagal syncope

18
Q

Provides Analgesia?

A

NO!

Anaesthesia (3 decks)

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