acellular life Flashcards

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1
Q

branch of biology deals with viruses

A

virology

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2
Q

characteristic of viruses(4)

A

1.GENOM (rna or dna)
2. protein coat(capsid)
3.reproduce only in living cell
4. lack organelles

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3
Q

why are viruses called Obligate intracellular parasites.

A

virus affecting a cell have control over the living cell

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4
Q

viruses destroyed by?

A

uv radiations

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5
Q

complete mature infectious virus called?

A

Virion

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6
Q

capsid made up of protein subunits known as?

A

capsomeres

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7
Q

the number of_____ is characteristic of a particular virus

A

capsomeres

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8
Q

who first discovered viruses and which method was used?

A

Iwanowski filtration.
bacteria couldnt pass through while agents responsible for rabies could.

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9
Q

who discovered that agent causing tobacco mosaic diseases was filterable?
A. charles chamberland
B. W.M stanley
C. Ivanowski
D. Edward jenner

A

ivanowski.

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10
Q

who was succesful in crystallising the tobacco mosaic virus

A

Stanley

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11
Q

what are prions?

A

infectious viral proteins that are self replicating. Cause mad cow adisease

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12
Q

what are viriods?

A

smallest infectious pathogens known.
composed of short single strand of RNA

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13
Q

double stranded dna virus

A

Poxviruses

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14
Q

single stranded rna viruses

A

togavirus(rubella virus), retrovirus, influenza virus

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15
Q

Single stranded DNA virus

A

Parvoviruses(mild rash)

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16
Q

Double stranded RNA viruses

A

Reoviruses(diarrhea)

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17
Q

how many known Plant viruses?

A

More than 2000 known.e.g T.M.V

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18
Q

animal virus that cause cancer in animals

A

Rous Sarcoma Virus

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19
Q

virus causing measles and mumps

A

Paramoxyvirus

20
Q

virus causes small pox

A

pox virus

21
Q

Bacteriophage virus function

A

parasitize the bacterial cells.
e.g Tadpoe virus T2 and T4

22
Q

size of viruses as compared to bacteria

A

10-1000x smaller.

23
Q

model viruses e.g

A

bacteriophage(bacteria eater)
flu virus
HIV

24
Q

structure of bacteriophage

A

.head(capsid)
.collar
.tail (contains lysozyme which digests bacterial cell wall)
. tail fiber( 6 fibers used to attach)

25
Q

bacteriphage life cycle steps

A

LYTIC CYCLE
1. attachment of virus to receptors
2.entry into the bacterial cell
3.Transcription of viral dna
4. replication
5. assembly of new parts
6. lysis and release

26
Q

lysogenic cycle

A

attachment and entry of genetic material(same as lytic cycle)
.viral dna binds to bacterial dna.
. bacterial cells divide by binary fission
.transferred to daughter cells.

27
Q

influenza virus structure

A

exists in 3 forms
single strand RNA
capsid have spikes for attachment

28
Q

HIV structure

A

enveloped with spikes
viral capsid
reverse transcriptaseviral rna (two single strands)

29
Q

herpes virus causative

A

herpes simplex which is dna enveloped.
vascular lesions(zakham) in layers of mouth lips skin

30
Q

mumps disease
(Cause and symptoms)

A

caused by paramoxyviruses
enveloped rna virus
symptoms; painful swelling of salivary gland

31
Q

influenza

A

enveloped rna
symptoms;fever cold sneezing

32
Q

measles

A

caused by paramyxoviruses
rna enveloped
fever and rash

33
Q

polio

A

rna IN SPHERICAL CAPSID
symptoms; inflammation of nervous system and paralysis

34
Q

Retroviruses description and types(2)

A

ssRNA virus AND contains Reverse transcriptase (rna to dna)

all retroviruses rna but NOT vice versa

.host specific e.g HIV
.non host specific: infect any host

35
Q

characteristics of retroviruses

A
  1. spherical
  2. enveloped
  3. size 100nm
  4. responsible for aids
36
Q

symptoms of HIV

A

.rare vascular cancer
.severe pneumonia
.dementia
.loss of immunity
.swollen lymph nodes
.fever.
.septicimia (blood infection)
.kaposi sarcoma (skin cancer)

37
Q

hiv infects which wbc

A

helper T lymphocytes.

38
Q

tranmission of hiv

A

breastfeeding
blood transfusions
contaminated syringes
sexual contact
passed genetically

39
Q

life cycle of HIV

A

virion (mature virus) attaches to CD4 receptors on t helper lymphocytes

virion enters and uncoats in cytoplasm

reverse transcriptase uses viral rna to make double strand DNA

DNA enters nucleus and into host chromosome.[PROVIRUS]

proviral dna—->RNA——-> proteins

40
Q

what is hepatitis (hepatic)

A

inflammation of liver due to viral infections, toxic agents or drugs

41
Q

hepatitis symptoms

A

jandice (yarkaan)
abdominal pain (pait dard)
liver enlargement
fatigue
fever

42
Q

hepatitis A causative agent and types

A

HAV, A NON ENVELOPED RNA VIRUS

two types
.Acute or mild
.Chronic

43
Q

hepatitis A mode of transmission and symptoms

A

.Faeces of infected person
.contaminated water

symptoms;
black urine
jaundice
loss of apetite
fatigue

44
Q

hepatitis B (serum hepatitis)
mode of transmmission/causative agent

A

HBV, DNA ENVELOPED

transmission;
mother to child during birth or feeding
sexual contact
blood serum

45
Q

which hepatitus known as infusion hepatitus and infectious respectively

A

C & A

46
Q

Hepatits C
mode/causative

A

HCV DNA* ENVELOPED
.blood transfusion
.mother to child
.sexual contact

47
Q

which hepatitis is defective

A

D