ACEI Flashcards
1
Q
Lotensin
- Dose
A
Benazepril
- D: 10mg QD or BID - 80mg QD
2
Q
Capoten
- Administration
- Frequency
A
Captopril
- Take on Empty stomach
Short t1/2 => TID
3
Q
Vasotec
- Form:
A
Enalapril
- The only comes in IV for this class
4
Q
Monopril
- Elimination:
- Safer in renal/hepatic impairment?
A
Fosinopril
- 50 and 50% in renal and hepatic
- Safer in renal impairment
5
Q
Prinivil
Zestril
A
Lisinopril
6
Q
Univasc
- Elimination:
- Safer in renal/hepatic impairment?
A
Moexipril
- 50 and 50% in renal and hepatic
- Safer in renal impairment
7
Q
Aceon
A
Perindopril
8
Q
Accupril
A
Quinapril
9
Q
Altace
- Form
A
Ramipril
- Only come in gel capsules. May mix with water, apple juice and apple sauce.
9
Q
Only ACEI come in gel capsules. May mix with water, apple juice and apple sauce.
A
Ramipril - Altace
10
Q
Mavik
A
Trandolapril
11
Q
ACEI ADEs
A
CAPTOPRIL C: Cough A: Angioedema P: Proteinuria T: Taste change: metallic, sweet, salty O: Orthostatic, hypoTN P: Pregnancy (C = 1st Tri/D = 2nd & 3rd Tri) R: Rash I: increase K L: leukocytosis (captopril)
12
Q
ACEIs are less effective in which population? Are refer in which disorders?
A
- African American. AA refers CCB and thiazide
- lipid disorders and sexual dysfunction
13
Q
What is the MOA of ACEI?
A
- Block the generation of angiotnesin II (a potent vasoconstrictor)
- Blocker of aldosterone secretion
- Decrease afterload due to aterial vasodilation
- Decrease pre-load
- Decrease intraglomerular capillary pressure
15
Q
What some cautions to ACEI?
A
- SCr > 3 mg/dL or CrCl < 30 mL/min
- SCr > 2.5 if DM
- HyperK
- Renal artery stenosis => hyperK
- Preg Cat D (All RAAS Med)
- Avoid K substitution, ARBs, and DRI
