ACE inhibitors- captopril

Question 1

what are ace inhibitors ( captopril) used to treat

Answer 1

diabetic nephropathy

Question 2

adverse reactions of ace inhibitors (captopril)

Answer 2

severe hypotension following 1st dose

dry nonproductive cough due to increase in bradykinin
rash/ metalic taste;
angioedema
hyperkalemia
neutropenia

Question 3

what is angioedema

Answer 3

swelling of mouth; throat due to inhibition of kinase II

Question 4

interventions when on ace inhibitor (captopril)

Answer 4

monitor BP following 1st dose
monitor and report dry cough
treat severe angina with IV epinephrine

Question 5

administration of ace inhibitor (captopril)

Answer 5

give 1hr before meals for adequate absorption

Question 6

client instructions when on ace inhibitor (captopril)

Answer 6

lie supine if lightheadedness
report rash and metallic taste
refrain from using potassium supplements; potassium containing salt substitutes

Question 7

contraindications of ace inhibitors (captopril)

Answer 7

teratogenic effects

Question 8

interactions with ace inhibitors (captopril)

Answer 8

potassium sparing diuretics ; potassium supplements; salt substitutes – increase risk for hyperkalemia
ace inhibitors may cause lithium toxicity