Abx renal adjustment

Question 1

Clarithromycin cut off

Answer 1

PO 500 mg BD

30 mL/min

Question 2

Amoxicillin/Augmentin cut off

Answer 2

Amoxicillin: PO 500-1000 TDS
Augmentin: PO 625 mg TDS or IV 1.2 g TDS

30 mL/min

Question 3

Ampicillin

Answer 3

IV 1.2 g q4-6 hours
50 mL/min

Question 4

Benzylpenicillin

Answer 4

IV 4MU q6 hours

50 mL/min

Question 5

Pip-tazo

Answer 5

IV 4.5 g q8 hours

<40 mL/min

Question 6

Cefuroxie

Answer 6

PO 250-500 mg q12 hour

<30 mL/min

Question 7

Cephalexin

Answer 7

PO 500-1000 mg q6-8 hours

<30 mL/min

Question 8

Cefazolin

Answer 8

IV 1-2 g q8 hours

<30 mL/min

Question 9

Ceftazidime

Answer 9

IV 1-2 g q8-12 hours

50 mL/min

Question 10

Cefepime

Answer 10

IV 2 g q8-12 hours

60 mL/min

Question 11

Meropenem

Answer 11

1g q8 hours

50 mL/min

Question 12

Ciprofloxacin

Answer 12

PO 500-750 mg q12 hours

<30 mL/min

Question 13

Levofloxacin

Answer 13

500-750 mg q24 hours

<50 mL/min

Question 14

Bactrim

Answer 14

PO 960 mg BD

30 mL/min

Question 15

Ethambutol and pyrazinamide

Answer 15

<30 mL/min follow 3TW dosing

Question 16

Acyclovir

Answer 16

Varicella:
800 mg 5x/day for 5-7 days

Herpes zoster:
800 mg 5x/day for 7-10 days

Herpes simplex:
400 mg TDS x 7-10 days

Bell’s palsy:
400 mg 5x/day x 10 days