Abx

Question 1

5 beta lactam classes

Answer 1

penicillins
cephalosporins
carbapenems
glyco/lipoglycopeptides

Question 2

Beta lactam MOA

Answer 2

cell wall inhibitors

Question 3

6 classes that inhibit protein production

Answer 3

tetracyclines
macrolides
aminoglycosides
nitrofurantoin
clindamycin
rifamycin

Question 4

3 drugs that inhibit replication

Answer 4

TMP-SMZ
Quinolones
metronidazole

Question 5

MC causes of CAP (2)

Answer 5

strep pneumo

h. flu

Question 6

atypical causes of CAP (3)

Answer 6

mycoplasma pneumoniae
legionella
chlamydia pneumoniae

Question 7

Outpatient Tx for CAP

Answer 7

PO macrolide

Question 8

inpatient tx for CAP.

Answer 8

PO macrolide + beta lactam (cefotaxime, ceftriaxone, ampicillin) +/- FLQ (moxi, levo)

Question 9

Tx for strep pneumo

Answer 9

high dose Pen G

Question 10

2 Tx options for uncomplicated acute cystitis

Answer 10

TMP-SMZ

Nitrofurantoin

Question 11

if local resistance to e. coli, what cystitis tx?

Answer 11

nitrofurantoin

no bactrim

Question 12

tx for complicated acute cystitis

Answer 12

cipro + urine cx

Question 13

cipro is effective against which 2 cystitis agents?

Answer 13

p. aeruginosa

enterobacteriaceae

Question 14

tx for acute pyelo with resistant organism

Answer 14

IV fluids + Carbapenem + urine cx

Question 15

tx for acute pyelo, non-resistant

Answer 15

piperacillin-tazobactam or FLQ

Question 16

3 adverse effects to FLQs

Answer 16

resistance, cartilage abnormality, prolonged QT

Question 17

PID tx

Answer 17

cephalosporin IM x 1 dose + PO doxycycline

Question 18

chlamydia tx…

Answer 18

doxy or azithro

Question 19

gonorrhoeae tx

Answer 19

ceftriaxone

Question 20

chlamydia with pregnancy tx

Answer 20

azithro

Question 21

DOC abx for pregnancy (2)

Answer 21

penicillins

cephalosporins

Question 22

which macrolides are category B teratogens?

Answer 22

erythromycin/azithromycin

Question 23

which 3 abx classes should always be avoided in pregnancy unless severe/life threatening infx…

Answer 23

FLQs, Tetracyclines, aminoglycocydes

Question 24

avoid ______ in the 1st trimester because it is a folate antagonist…

Answer 24

trimethoprim

Question 25

avoid _____ at term for bile conjugation interference

Answer 25

sulfas

Question 26

avoid ______ at term due to risk of neonatal hemolysis

Answer 26

nitrofurantoin

Question 27

dosing considerations for pregnancy…

Answer 27

avoid in 1st trimester, shortest duration

Question 28

2 MC pathogens for bacterial meningitis

Answer 28

strep pneumo

n. meningitides

Question 29

empiric tx of bacterial meningitis

Answer 29

ceftriaxone/cefotaxime + vanco

Question 30

cephalosporins should be avoided in ______ patients

Answer 30

PCN allergy

Question 31

2 most common causes of cellulitis…

Answer 31

staph aureus, s. pyogenes

Question 32

empiric tx for cellulitis

Answer 32

clinda, TMP-SMZ, tetracyclines

Question 33

clindamycin tx confers greater risk for…

Answer 33

c. diff

Question 34

which drug class is hapatotoxic and causes impaired fetal bone/teeth development

Answer 34

tetracyclines

Question 35

tetracyclines are contraindicated in children under…

Answer 35

8 yo

Question 36

which tetracycline causes blue-black hyperpigmentation

Answer 36

minocycline

Question 37

3 MRSA abx…

Answer 37

vanco, daptomycin, oxazolidinone (linezolid, tedizolid)

Question 38

which abx is effective against c diff?

Answer 38

vanco

Question 39

vanco can cause _____syndrome

Answer 39

red man syndrome