Abx Flashcards
Agents to treat anaerobes
Zosyn Ciprofloxacin Clindamycin Flagyl Cefuroxim, Cefoxitin, Cefotetan Augmentin
Agents to treat atypicals
Fluoroquinolones
Macrolides
Treat CA-MRSA?
Clindamycin Doxycycline Bactrim DS Linezolid Rifampin
Why not use a macrolide alone for pneumonia?
No longer gets strep pneumonia, it is used to cover ATYPICALS while the cephalosporin is added to cover strept pneumonia
DOC for afebrile neutropenia?
HIGH DOSE cefepime (2 grams)
*if MRSA, can add Vanco
No dose adjustment for renal impairment
Ceftriaxone Azithromycin Nafcillin, Oxacillin Clindamycin Doxycyline Moxifloxacin Linezolid
Acute pancreatitis
*up to 20% get infections
Start abx unless cultures are negative
Ciprofloxacin
Primaxin (imipenem/cilastatin)
Cefuroxime
Pre-op with PNC allergy and surgery where gram(-) may be relevant?
Cipro 400 mg AND Flagyl 500 mg
*if gram(+), i.e., skin, then Vanco 1 gram or Cipro 600 mg
Most common gram(-) in sepsis?
E. coli & pseudomonas
Cephalosporins w/ pseudomonas coverage?
Fortaz (ceftazidime); 3rd gen, very little gram(+)
Maxipime (cefepime); 4th gen
Teflaro (ceftaroline); 5th gen
Antistaphylococcal penicillin’s
Nafcillin & Oxacillin
Skin infection PO treatment:
Bactrim or Cleocin
Travelers diarrhea
E. coli (80%), C. jejuni
Fluoroquinolones (+ loperamide)
Prego/children: Bactrim or Azithromycin
SIRS criteria
*at least 2 meets SIRS criteria
Tempt > 100.4 OR <96.8
HR > 90
RR > 20 OR PaCO2 <32
WBC >12,000, < 4,000, OR bands >10%
Cephalosporins w/ anaerobic coverage
Ceftin, Zinacef (cefuroxime); 2nd gen
Mefoxin (cefoxitin); 2nd gen
Cefotan (cefotetan); 2nd gen
Cephalosporins w/ anaerobic coverage
Ceftin, Zinacef (cefuroxime); 2nd gen
Mefoxin (cefoxitin); 2nd gen
Cefotan (cefotetan); 2nd gen
Cephalosporin that covers MRSA and pseudomonas
Teflaro (ceftaroline); 5th gen
*also covers some gram(+)
Agents used for pseudomonas aeruginosa
Zosyn
Ceftazidime, Cefepime, Ceftarloine
Cpriofloxacin, Levofloxacin, Moxifloxacin (not as active as cipro and levo)
CARBAPENEMS
Aztreonam
Aminoglycosides (Tobramycin = best of the AG’s)
VRE. faecalis vs. faecium tx
CONFIRM THIS CARD
Both:
Penicillin G
Ampicillin
Linezolid
VRE UTI other than faecalis or faecium – doxycycline 100 mg BID (PO)
DOC for gonoccal conjunctivitis
3rd gen cephalosporins
UTI
Sexually active women: E. coli (80%), staph saprophyticus
Acute cystitis (uncomplicated): Bactrim DS, if >20% resistance or sulfa allergy: Cipro, Levo, or Nitrofurantoin
Acute pyelonephritis (uncomplicated): Fluoroquinolones (1st line) x 5-7days
SEVERE: Amp + Gent or Zosyn or CARBAPENEMS x 14 days
Prego: Beta-lactams or nitrofurantoin
