Abnormalities of White Cells Flashcards
What are the four steps involved in Phagocytosis?
Chemotaxis
Opsonization
Ingestion
Killing
Which Phagocytosis stage emits chemicals that are sensed by the neutrophils?
Chemotaxis
Which Phagocytosis stage coats a foreign body with a chemical preparing it to be ingested?
Opsonization
What is a patient fighting when Neutrophils are present?
Bacterial Infection
What is a patient fighting when Eosinophils are present?
Allergic Reaction/Infection
What is a patient fighting when Lymphocytes are present?
Viral Infection
What are the inclusions that we see regarding Neutrophils in a peripheral smear?
Left Shift
Toxic Granulation
Toxic Vacuolization
Dohle Bodies
What is Ehrilchia Chaffeensis (Human Monocyte Ehrlichiosis)?
Tick diseases caused by two type of Rickettsia
Acquired
What is May-Hegglin Anomaly characteristic of?
Thrombocytopenia and Giant Platelets
What is Alder-Reilly Anomaly characteristic of?
Coarse Dark granules
What is Pelger-Huet Anomaly characteristic of?
Dumb bell shaped nucleus
What is Chediak-Higashi Anomaly characteristic of?
Reduced Chemotaxis and killing function
Albinism
Photphobia
What is normal to see in children age 1-4?
Relative Lymphocytosis
What causes Infectious Mononucleosis and what are the symptoms?
Epstein-Barr virus
Sore Throat, Fatigue, Anorexia, Fever, Large Lymph nodes
Reactive Lyphocytes
10-60% in peripheral smear
How do we define Leukocytosis?
Absolute increase in total WBC count
What do we mean when we say a “Left Shift” in regards to WBCs?
Bone marrow sends out younger cells
What happens in a Leukemoid reaction?
An exaggerated response to infections and inflammation
Cells are younger than Meta, but rarely includes blasts
What is a patient fighting when we see Monocytes?
A chronic Infection
What amount of Reactive Lymphocytes do we see in a diagnosis of Infectious Mononucleosis?
10% - 60% Reactive Lymphocytes do
