Abnormal coagulation Flashcards
1
Q
Heparin
A
Prevents activation factors 2, 9, 10 and 11
2
Q
Warfarin
A
Affects synthesis of factors 2, 7, 9 and 10
3
Q
DIC
A
Factors 1, 2, 5, 8 and 11
4
Q
Liver disease
A
Factors 1, 2, 5, 7, 9, 10 and 11
5
Q
Haemophilia
A
Increased APTT, normal PT and normal bleeding time
6
Q
von Willebrand’s disease
A
Increased APTT, normal PT and increased bleeding time
7
Q
Vitamin K deficiency
A
Increased APTT, increased PT and normal bleeding time
8
Q
Tranexamic acid
A
Inhibits plasmin -> prevents fibrin degradation
9
Q
Tranexamic acid
A
Inhibits plasmin -> prevents fibrin degradation
10
Q
Which factors are sensitive to temperature?
A
Factors V and VIII
