ABEM Recert Exam pt. 4 Flashcards
Macule: Definition
<1 cm, non-palpable
Papule: Definition
<1cm, palpable
Patch: Definition
> 1cm, non-palpable
Plaque: Definition
> 1cm, palpable
Vesicle: Definition
<1cm papule with clear fluid
Bullae: Definition
> 1cm plaque filled with clear fluid
What conditions is Nikolski’s sign seen with?
SSSS, TEN/SJS, Pemphigus Vulgaris
Bullous pemphigoid vs Pemphigus vulgaris: How to diff?
Bullous pemphigoid doesn’t have Nikolski’s sign
HUS-TTP: Rx
Exchange transfusion
NO PLATELETS, since it’s a consumptive process
Bullous pemphigoid and Pemphigus vulgaris: Appearance
Large, flat bullae
Leptosporosis: How is it transmitted?
Through contact with urine in a contaminated water source (e.g. exposure as a cattle rancher or through recreation in water)
Babesiosis: si/sx
Similar to malaria
Babesiosis: Geographic distribution
Found in New England
Babesiosis: Pathophysiology
Intracellular parasite which infects RBCs
Yersinia pestis (plague): Appearance
Patients have a bubo (infected, tender, swollen lymph node)
Tularemia: Geographic distribution
Found world-wide, but often in California on board questions
Tularemia: Reservoir, vector and how it’s spread
Reservoir = Rabbits
Vector = Fleas / ticks
Can’t be spread human to human
Tinea: Rx
Must use oral antifungal if involves hair or nails, otherwise can use topical
SJS/TEN vs SSSS: How to diff?
SSSS usually doesn’t have mucous membrane involvement
SJS/TEN: Typical cause
Medications (often sulfa or antiepileptic)
Hemophilia A: Cause
Factor 8 deficiency
Hemophilia B: Cause
Factor 9 deficiency (Christmas disease)
Will PT, PTT, or both be abnormal in hemophilia?
Only PTT is abnormal
von Willebrand’s disease: Rx
DDAVP for mild disease
Factor 8 for severe disease
ITP: Rx
Steroids
NO platelets
TTP: si/sx
FAT-RN Fever Anemia Thrombocytopenia Renal involvement Neurologic changes
TTP: Rx
Plasma exchange transfusion
Steroids
NO platelets
Microcytic anemia: Causes
Lead
Iron deficiency
Sideroblastic
Thalassemia
Normocytic anemia: Causes
Decreased production of normal RBCs (anemia of chronic disease, aplastic anemia)
Destruction of normal RBCs (hemolysis, blood loss)
Uncompensated increase in plasma volume (pregnancy, fluid overload)
Macrocytic anemia: Causes
Alcohol
B12/Folate deficiency
COPD
G6PD
AML vs CLL: How to diff
AML usually dosen’t have lymphadenopathy, CLL usually does
CLL always has increased WBCs, AML may have low, normal, or high WBCs
Optic neuritis: si/sx
Eye pain
Blurred vision
APD
Is unilateral, never bilateral
Normal ESR: How to calculate
(age + 10) / 2
Encephalitis: Definition
Fever
Headache
Neurologic changes
Encephalitis: MRI findings
Edema and/or hemorrhage in temporal lobe
Epidural abscess: Causative agent
Most are Staph aureus
Encephalitis: CSF findings
Increased protein