AA metabolism, Urea Cycle Flashcards

1
Q

What is the alpha keto cousin of aspartate?

A

oxaloacetate

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2
Q

What is the alpha keto cousin of alanine?

A

pyruvate

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3
Q

What is the alpha keto cousin of glutamate and glutamine?

A

alpha ketoglutarate

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4
Q

_____ and ____ are used to transport NH3 groups between tissues

A

glutamine and alanine

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5
Q

What is the function of glutamine synthetase?

A

It synthesizes glutamine from glutamate. It uses NH3 and ATP.

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6
Q

What is the function of carbamoyl-phosphate synthetase-I?

A

adds 2 ATP, bicarbonate, and free ammonia to produce carbamoyl-phosphate

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7
Q

What is the function of glycine synthase?

A

It produces glycine from N5. N10-methyl THF

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8
Q

What is the function of glutamate dehydrogenase?

A

Converts glutamate to alpha ketoglutarate

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9
Q

What is the function of glutaminase?

A

Converts glutamine to glutamate

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10
Q

In the liver, glutaminase generates ___ for secretion

A

NH3

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