A2 synthesis routes Flashcards
alkane to haloalkane
reagent: halogen
conditions: uv light
haloalkane to alcohol
reagent: NaOH (aq)
conditions:
alcohol to haloalkane
reagents: sodium halide/ H2SO4
primary alcohol to aldehyde
reagent: H+/K2Cr2O7
conditions: distillation
aldehyde to primary alcohol
reagent: NaBH4
primary alcohol to carboxylic acid
reagent: H+/K2Cr2O7
conditions: reflux
aldehyde to carboxylic acid
reagent: H+/K2Cr2O7
conditions: reflux
carboxylic acid to acyl chloride
reagent: SOCl2
conditions:
acyl chloride to carboxylic acid
reagent: cold H2O
conditions:
haloalkane to nitrile
reagent: CN-
conditions: ethanol, reflux
haloalkane to amine C-NR2
reagent: ethanolic ammonia
conditions: heat
nitrile to amine
reagent: H2
conditions: nickel catalyst
secondary alcohol to ketone
reagent: H+/ K2Cr2O7
conditions: reflux
ketone to secondary alcohol
reagent: NaBH4
conditions:
ketone to hydroxynitrile
reagent: NaCN (aq)/H+ (aq)
conditions:
hydroxynitrile to amine
-OH -C≡N C-NR2
reagent: H2
conditions: Ni catalyst
aldehyde to hydroxynitrile
reagent: NaCN (aq)/ H+ (aq)
conditions:
nitrile to carboxylic acid
reagent: H2O/ HCl
conditions: heat
hydroxynitrile to carboxylic acid
reagent: H2O/ HCl
conditions: heat
acyl chloride to primary amide
reagent: NH3 (ammonia)
conditions:
acyl chloride to secondary amide
reagent: primary amine
conditions:
alkene to alkane
reagent: H2
conditions: Ni catalyst
alkene to haloalkane
reagent: hydrogen halide
conditions:
alkene to alcohol
reagent: steam
conditions: H3PO4
alcohol to alkene
reagent: H3PO4 or H2SO4
conditions: heat
alcohol to ester
reagent: carboxylic acid/ concentrated H2SO4 or acid anyhydride
conditions:
carboxylic acid to ester
reagent: alcohol
conditions: concentrated H2SO4
ester to carboxylic acid
reagent: dilute acid
conditions: heat
acyl chloride to ester
reagent: alcohol
conditions:
ester to carboxylate
reagent: OH-
conditions: heat