A. REUMATOIDE Flashcards

1
Q

fisiopatologia

A

-HLA DR
-tabagismo e infeccoes periodontais

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2
Q

manifestacoes articulares

A

-Poliartrite CRONICA SIMETRICA ADITIVA
-Rigidez >1h
-interfalageanas PROXIMAIS e punhos

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3
Q

mao de A. reumatoide

A

-Desvio ULNAR a esquerda
-Pescoco de cisnei: extensao da PROXIMAL com flexao DISTAL
-Botoeira :extensao DISTAL e flexao PROXIMAL
-comeco: sinovite 2 a 3 meta

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4
Q

Extraarticulares

A

-Nodulos : + comum
-Xeroftalmia
-Mielopatia cervical: subluxacao atlantoaxial
-Derrames ( exudato )
-Anemia normo
-sx de FELTY : A.REUMATOIDE + esplenomegalia + neutropenia

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5
Q

RX

A

-Precoce: osteopenia (preto )
-Tardia: erosao marginal ( mordida de maca )

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6
Q

DX

A

-> 6 pts
-FR e ANTI ccp ( + ESPECIFICO)
->6 SEM
-laboratorio elevado
-Clinica classica

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7
Q

Tto

A

-AINES e corticoides
-DMARDS: alterada prognotsico e mantem por vida

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8
Q

DMARDS

A

-Sintetico : metotrexato (escolha e inicial ) e hidroxicloroquina
-Imunobiologicos: ANTI TNF

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9
Q

se nao funciona só com metotrexato , conduta

A

-combina outro sintetico
-combina com biologico
-associa com rituximabe

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10
Q

Caracteristicas da Fibromialgia

A

-Dor cronica, fadiga e alteracao de sono
-Multiplas queixas
-Mulheres adultas
-Nao autoimune, nao inflamatoria sem associacao com qualquer alteracao

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11
Q

Caracteristicas da esclerose sistemica

A

-Triade : autoimune + fibrose + vasculopatia
-Fenomeno de raynauld é o + comum
-Aumenta risco de cancer esofagico
-Espessamento cutaneo , esclerodactilia e doenca intersticial
-Tto: predinisona + metrotrexato

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12
Q

epidemio

A

-30 a 60a em mulheres

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13
Q

Laboratorio

A

-eleva VHS e PCR
-ANTICCP: MAIS ESPECIFICO
-FAN: sensibilidade semelhante ao anticcp

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