9b.) GI Emergencies Flashcards

1
Q

What is peritonitis?

A

Inflammation of the serosal membrane that lines the abdominal cavity (the peritoneum)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Peritoneal cavity is usually a sterile environment; true or false?

A

True

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Describe how patients with peritonitis will often lie

A

Lie very still, any movement is painful

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

State and describe the two types of peritonitis

A
  • Primary: inflammation due to spontaneous bacterial invasion of peritoneum- causses infection of the ascitic fluid in peritoneum
  • Secondary: inflammation due to foregin substance entering peritoneal cavity perforation or gangrene of intra-abdominal or retroperitoneal structure (note: can have bacterial and non-bacterial causes)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Who is primary peritonitis commonly seen in?

A

Patients with end stage liver disease (cirrhosis)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Describe how ascites form in patients with end stage liver disease (cirrhosis)

A
  • Cirrhosis compresses veins in liver
  • Causes portal hypertension which increases pressure in veins draining gut- increases hydrostatic pressure of veins
  • Cirrhosis also causes decreased liver function leading to hypoalbuminaemia- decreases oncotic pressure in veins
  • Net movement of fluid down pressure gradient out of veins and into peritoneum
  • Problem exacerbated by RAAS responding to decreased intravascular volume
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Describe how someone with peritonitis might present

A
  • Abdo pain
    • Can come on gradually or acutely (if acute likley to be perforated viscera)
    • Will lie still with knees flexed
  • Shallow breathing
  • Fever
  • Vomitting
  • Distension & swelling
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

How do you diagnose primary peritonitis?

A
  • Aspirate ascitic fluid
  • Neutrophil count >250cells/mm^3
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

State some common causes of secondary bacterial peritonitis

A
  • Peptic ulcer disease- ulcer perforated
  • Perforated appendix
  • Diverticulitis- divertuclum perforated
  • Post surgery
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

State some comon causes of secondary non-bacterial peritonitis

A

Usually caused by blood entering peritoneal cavity

  • Tubual pregnancy that bleeds (remember peritoneal cavity is not closed in females so blood can travel from tubes to peritoneum)
  • Ovarian cyst
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Secondary peritonitis can be bacterial or non-bacterial; explain the difference

A
  • Bacterial: caused by bacteria which often enters due to lack of integrity of GI system
  • Non-bacterial: often due to blood entering peritoneal cavity (blood is highly irritant to peritoneal cavity)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Describe the typical presen

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Describe how we treat peritonitis (3)

A
  • Control infectious source (e.g. surgery if perforation)
  • Eliminate bacteria using antibiotics
  • Maintain organ system function
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Define bowel obstruction

A

Mechanical or functional problem that inhibits the normal movement of gut cotents; it can affect small or large intestine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Bowel obstruction only affects the elderly; true or false?

A

FALSE- bowel obstruction can affect all ages

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

State the 3 most common causes of bowel obstruction in paediatrics

A
  • Meconium ileus: the meconium is blocking the ileum
  • Intestinal atresia: congenital malformation in which segment of intestine failed to develop properly hence causing a complete blockage or lack of continuity e.g. pyloric stenosis
  • Intussusception: part of intestine folds into segment next to it
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

State 2 most common causes of bowel obstruction in adults

A
  • Post op adhesions
  • Incarcerted hernias: hernia that cannot be moved back in place- pinchign action can obstruct bowel (see image)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Describe intussusception, include:

  • What occurs
  • Causes
  • How far can intussusception extend
  • Complications
  • Symptoms
  • Treatment
A
  • One part of gut tube telescopes/folds into an adjacent section
  • Cause not well known, think:
    • Potential motility issues
    • ‘Lead point’: mass (could be lymph node, Meckels diverticulum etc..) that precipitates telescoping action
  • Extend as far as prolapsing out of rectum
  • Complications:
    • Impair lymphatic & venous drainage -> oedema
    • Oedema can impair arterial supply -> infarct
  • Symptoms:
    • Abdo pain
    • Vomitting
    • Haematochezia (rectal bleeding)
    • Mucus
  • Treatment:
    • Air enema
    • Surgery
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Describe how someone with small bowel obstruction may present

A

Often start suddenly:

  • Nausea/vomitting (bilioius) = early symptom
  • Peri-umbilical pain
  • Abdo distension
  • High pitched bowel sounds on auscultation
  • Absolute constipation= late symptom
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

State 2 possible causes of small bowel obstruction

A
  • Hernias
  • IBD causing stenosis
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Which population do large bowel obstructions typically affect?

A

Older generation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

State some common causes of large bowel obstruction

A
  • Colon cancer
  • Diverticular disease- can lead to strictures
  • Volvulus- sigmoid, caecal (loop of intestine twists around itself and it’s mesentery)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Most large bowel obstructions caused by cancer occur distal to what flexure?

A

Distal to splenic flexure

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

What imaging can we use to aid diagnosis of bowel obstruction?

A

CT

Abdominal x-ray

????

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

Describe how someone with large bowel obstruction might present

A
  • Peri-umbilical or suprapubic pain
  • Abdo distension
  • Diarrhoea or constipation (early symptom)
  • Nausea or vomitting (late symptom)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

Describe volvulus, include:

  • What it is
  • Where it is most common
  • Causes
  • Consequences of caecal volvulus
A
  • Part of colon twists around itself and its mesentery
  • Most common in sigmoid colon (60%) and caecum
  • Causes:
    • Overloaded sigmoid colon (constipation) as extra mass elonages sigmoid meaning there is a relatively smaller mesenteric attachment
  • Caecal volvulus leads to small and large bowel obstruction
27
Q

Compare small and large bowel obstruction, consider:

  • Age typically presents in
  • Abdo pain
  • Vomitting
  • Constipation
A
  • Small bowel- often younger
  • Large bowel- often older age group (because causes of large bowel obstruction develop over time)
28
Q

What is acute mesenteric ischaemia?

A

Symptomatic reduction in blood supply to GI tract

29
Q

State and describe 4 causes of acute mesenteric ischaemia

A
  • Acute occlusion: often due to emboli (50% are in SMA)
  • Non-occlusive mesenteric ischaemia: due to low cardiac output
  • Mesenteric venous or arterial thrombosus: venous thrombosis can do it as it can block venous end and cause back log of pressure (e.g. due to systemic coagulopathy, malignancy)
  • Vasculitis or vasoconstriction
30
Q

Describe how acute mesenteric ischaemia may present

A
  • Abdominal pain typically 30 mins after eating and can last for hours
    • Disproportionate to clinical findings (e.g. no clinical findings but pt in severe pain)
    • Often on left side as blood supply to splenic flexure is most fragile
  • Nausea & vomitting
  • Fever
  • Haematochezia (15%)
  • Diarrhoea
31
Q

State 3 investigations we can do to support diagnosis of acute mesenteric ischaemia

A
  • Blood test: metabolic acidosisdue to increased lactate levels from anaerobic respiration
  • Errect chest x-ray: check for perforation
  • CT angiography: inject dye into vessels supplying gut

NOTE: CT is the test of choice out of these

32
Q

Describe how we treat acute mesenteric ischaemia

A

Treatment depends on severity:

  • Badly ischaemic bowel: surgery to remove damaged part and resect bowel
  • If we can save bowel: surgical embolectomy, angioplasty or use of thrombolytic agents
33
Q

Mortality of acute mesenteric ischaemia is high; true or false?

A

True. Mortality is high particulary in older patients with other co-morbidities and if it is an arterial thrombosis

34
Q

What is the most common cause of upper GI bleeding?

A

Peptic ulceration

35
Q

Which artery is most likely to be ruptured in a duodenal ulcer?

A

Gastro-duodenal artery as it lies behind first part of duodenum

36
Q

Where are gastric ulcers most common?

A
  • Lesser curve
  • Antrum
37
Q

What artery could a gastric ulcer in body of stomach erode into?

A

Splenic artery

38
Q

Describe the path blood may take in oesophageal varices

A
39
Q

Most uppper GI bleeds stop spontaenously; true or false?

A

True; 80% stop spontaneously

40
Q

Oesophageal varies are the most common problem associated with portal hypertension; true or false?

A

True, 90% develop varices and 30% of those bleed

41
Q

What divides the greater sac into supracolic and infracolic regions?

A

Transverse mesocolon

42
Q

Peritonitis can be sterile or infectious; true or false?

A

True

43
Q

Why might someone with peritonitis get shoulder tip pain?

A
  • Peritonitis= inflammation of peritoneum
  • Inflamed peritoneum or ascites may irritate diaphragmn
  • Diaphragm innervated by phrenic nerve (C3, C4, C5)
  • Dermatomes over shoulder
44
Q

Is the descending colon narrow than the ascending colon?

A

Yes

45
Q

What are intra-abdominal adhesions?

How do they form?

State another potential consequence of adhesions, besides bowel obstruction

A
  • Abnormal fibrous bands of tissue between organs or tissues (e.g. can be between two sides of lumen) or both in the abdominal cavity connecting structures which are usually separated
  • Damage to mesothelium causes capillary to leak leading to exudation of fibrinogen
  • Secondary infertility
46
Q

Explain why adhesions form

A
  • Damage to mesothelium
  • Capillary bleeding lead to exudation of fibrinogen
47
Q

Describe how a competent ileo-caecal valve increases the chance of ischaemia and perforation

A
  • If valve is competent the colon cannot decompress proximally
  • Closed loop obstruction
  • Increases chance of ischaemia and perforation
48
Q

What does this image show?

A

Volvulus

“Coffee bean sign”

49
Q

How can we determine which is the large and which is the small intestine?

A
  • Left= small
  • Right= large

Because….

  • Small intestine lines should go all way across ‘plicae circulares’
  • Large intestine lines shouldn’t go all way across ‘haustra’
  • Small intestine central
  • Large intestine at periphery
50
Q

How can we treat oesophageal varices?

A
  1. Ligation: band around the bulging varices to prevent further blood going in and rupture. Varices evetnually fall off/drop off
  2. (if can’t control by ligation) Transjugular intrahepatic portosystemic shunt (TIPS): expandable metal placed in liver to bridge portal vein to hepatic vein to reduce portal pressure and hence reduce variceal pressure
  3. Vasopressin agonist to reduce portal venous pressure and pressure in varices e.g. terlipressin
51
Q

How do we treat upper GI bleeding?

A
  • Depends on cause
  • Non-variceal bleeding should be treated with endoscopy, clips, coagulation and thrombin
  • PPI’s play role after initial therapy
52
Q

Who is acute mesenteric ischaemia more comon in? (2)

A
  • Females
  • Cardiovascular risk factors/history of peripheral arerial disease
53
Q

What is a triple A?

A
  • Abdominal aortic aneuryseum
  • Permanent pathological dilation of the aorta with a diameter 1.5 times > than the expected anteroposterior diameter of that segment given the patients body size and sex
  • NOTE: most commn threshold is if infrarenal aorta (as this is where most of them are) is 3cm or more (should be 1.5cm)
54
Q

Where are the majority of abdominal aortic aneuryseums?

A

Infrarenal

55
Q

Explain how triple A’s usually arise

A
  • Degeneration elastin and collagen in media layer of arterial wall
  • Lumen gradually starts to dilate
56
Q

State some risk factors for triple A

A
  • Male
  • Age >65
  • Inherited risk
  • Increasing age
  • Smoking
  • Peripheral atherosclerotic vascular disease
57
Q

Most triple A’s are symptomatic; true or false

A

False; most of them are asymptomatic and found accidentally

58
Q

Describe how a triple A (that hasn’t ruptured) may present

A
  • Abdominal and back pain
  • Symptoms due to compression of other structures e.g. nausea, urinary frequency
  • Pulsatile mass in abdomen
59
Q

Describe how a triple A that has ruptured may present

A
  • Severe abdominal pain (+/- flank and groin pain)
  • Back pain
  • Pusatile abdominal mass
  • Transient hypotension- syncope
  • Rapid HR
  • Shock
60
Q

What’s the prognosis for someone with a ruptured triple A?

A

65% die before they get to hospital due to sudden cardiovascular collapse

61
Q

State 4 ways we can diagnose triple A

A
  • Physical examination: pulsatile mass in abdomen (only felt in <50% cases)
  • Ultrasonography
  • CT
  • Plain x-ray: useful if aneuryseum has calcified as we can see this clearly on x-ray
62
Q

State how we treat an unruptured triple A (5)

A
  • Non surgical:
    • Smoking cessation
    • Hypertension control
  • Surveillance of AAA:
    • >5.5cm refer to vascular surgeons
  • Surgery:
    • Endovascular stent graft: reline aorta with an endograft (metallic stent)- inserted through femoral artery. Seals beloow renal arteries and above common iliac
    • Open surgical repair: clamp aorta, ope anueryseum, remove debris, suture in synthetic graft
63
Q

How would we treat a ruptured triple A?

A

Emergency resuscitation & surgery