9.3 citric acid cycle

Question 1

pyruvate is broken down into

Answer 1

3 CO2 molecules

Question 2

step 1;

Answer 2

acetyl CoA adds its acetyl group to oxaloacetate

–produces citrate

Question 3

step 2:

Answer 3

citrate is converted to its isomer (isocitrate)

by removing 1 water molecule and adding another

Question 4

step 3:

Answer 4

isocitrate is oxidized and electrons are used for->
NAD+ is reduced to NADH
-the resulting cmpd loses a CO2 molecule

Question 5

step 4:

Answer 5

• -lose another CO2
• -NAD+ reduced to NADH
• -remaining molecule attached to CoA by unstable bond

Question 6

step 5:

Answer 6

CoA is displaced by a phosphate group

• -phosphate group transferred to GDP
• -forming GTP
• -can be used to generate ATP

Question 7

step 6:

Answer 7

2 hydrogens are transferred to FAD

• -forming FADH2
• -oxidizes succinate

Question 8

step 7:

Answer 8

–water molecule addition rearranges binds in substrate

Question 9

step 8: v

Answer 9

substrate is oxidized

–reducing NAD+ to NADH and regenerates oxaloacetate

Question 10

results

Answer 10

• -3 NAD+ -> NADH
• -6 electrons transfered to FAD -> FADH2
• -GTP
• -ATP