92 Moderate to Severe Allergic Reaction

Question 1

What are the INDICATIONS for the ALLERGIC REACTION medical directive?

Answer 1

Exposure to a probable allergen
Signs and symptoms of a moderate to severe allergic reaction

Question 2

What are the CONTRAINDICATIONS for EPINEPHRINE in the ALLERGIC REACTION medical directive

Answer 2

Allergy to epinephrine

Question 3

What are the CONDITIONS for EPINEPHRINE in the ALLERGIC REACTION medical directive?

Answer 3

For anaphylaxis only

Question 4

What is the MAX dose for EPINEPHRINE in the ALLERGIC REACTION medical directive?

Answer 4

0.5mg

Question 5

What is the DOSE for EPINEPHRINE in the ALLERGIC REACTION medical directive?

Answer 5

0.01mg/kg up to 0.5mg

Question 6

What is the dosing INTERVAL for EPINEPHRINE in the ALLERGIC REACTION medical directive?

Answer 6

5 minutes

Question 7

How MANY doses can you give for EPINEPHRINE in the ALLERGIC REACTION medical directive?

Answer 7

2

Question 8

What is the ROUTE of administration for EPINEPHRINE in the ALLERGIC REACTION medical directive?

Answer 8

IM

Question 9

What is the MAXIMUM dose weight for EPINEPHRINE in the ALLERGIC REACTION medical directive?

Answer 9

50kg

Question 10

Why is Epinephrine ideal for anaphylaxis in comparison to Diphenhydramine?

Answer 10

Relieves upper airway obstruction
Fixes HoTN

Question 11

What type of shock is anaphylaxis

Answer 11

Distributive

Question 12

What causes shock in anaphylaxis?

Answer 12

Mast cells release histamine creating a widespread inflammatory response

Question 13

How does the body respond to histamine

Answer 13

Vasodilation
Increased capillary permeability
WBC produce leukotrienes

Question 14

What is the DRUG CLASS of EPINEPHRINE?

Answer 14

Sympathomimetic
Adrenergic agonist

Question 15

What receptors does epinephrine affect?

Answer 15

Alpha 1
Alpha 2
Beta 1
Beta 2

Question 16

What are the effects of EPINEPHRINE for ANAPHYLAXIS

Answer 16

A1: vasocontricts arterioles in the skin, increases preload
B1: positive inotrope, dromotrope, chronotrope
B2: bronchodilates the lungs

Inhibits histamine, stabilizes mast cells permeability

Question 17

Epinephrine administration or IV access

Answer 17

Epinephrine administration

Question 18

What are the CONTRAINDICATIONS for DIPHENHYDRAMINE in the ALLERGIC REACTION medical directive?

Answer 18

Allergy to diphenhydramine

Question 19

What are the CONDITIONS for DIPHENHYDRAMINE in the ALLERGIC REACTION medical directive?

Answer 19

over 25 kg

Question 20

What is the DIVISIONAL WEIGHT for DIPHENHYDRAMINE in the ALLERGIC REACTION medical directive?

Answer 20

25kg, 50kg

Question 21

What is the DOSE for 25kg-50kg DIPHENHYDRAMINE in the ALLERGIC REACTION medical directive?

Answer 21

25mg

Question 22

What is the DOSE for 50kg DIPHENHYDRAMINE in the ALLERGIC REACTION medical directive?

Answer 22

50mg

Question 23

What is the dosing INTERVAL for DIPHENHYDRAMINE in the ALLERGIC REACTION medical directive?

Answer 23

N/A

Question 24

How MANY doses can you give for DIPHENHYDRAMINE in the ALLERGIC REACTION medical directive?

Answer 24

1

Question 25

What is the ROUTE of administration for DIPHENHYDRAMINE in the ALLERGIC REACTION medical directive?

Answer 25

IV/ IM

Question 26

What is the DRUG CLASS of Diphenhydramine?

Answer 26

Antihistamine
Anticholinergic

Question 27

How does Diphenhydramine affect histamine receptors

Answer 27

non-selective and competitive
binding to H1 receptors

Question 28

How does diphenhydramine work?

Answer 28

Competitively binds to H1 receptors
Reduces the amount of histamine
Mast Cell stabilizer

Question 29

What does Diphenhydramine not fix in allergic reactions?

Answer 29

Hypotension
Airway swelling