9.1- chemical control Flashcards
what does homeostasis mean?
-maintenance of a constant internal environment
-in humans out internal environment is made up of fluid surrounding our cells, features of this fluid must remain constant
-involves constant changes around an optimum point
3 things which can fluctuate in order to keep homeostasis
- temp
- pH
- water potential
importance of homeostasis; temp and pH
-changes in pH and temp effect proteins e.g. enzymes+ channel proteins
-changes can cause reduction in rate of reaction (reduced kinetic energy) or denaturation
-
importance of homeostasis; water potential
-changes in water potential of tissue fluid or blood can cause a change in volume of cells due to osmosis
-particularly influenced by glucose conc which effects respiration
4 factors of the control mechanism
1.optimum- point at which reaction works best
2.receptor- detects change from optimum
3.coordinator- links receptor and effector
4.effector- muscle or gland which brings changes to return to optimum
what is negative feedback?
-system deviates from optimum
-change is detected by reeptor
-change is produced which returns system back, closer to optimum
what is positive feedback?
-system deviates from optimum
-change detected by receptor
-change then produced which causes an even greater deviation from optimum
-e.g. oxytocin makes uterus contract harder, baby pushes against and stretches cervix, more released
endocrine glands and hormones
-hormones are organic chemicals produced in an endocrine gland
-they travel in blood and can be widespread or targeted
-protein or peptide hormone examples are insulin, ADH
-steroid hormone examples are oestrogen and progesterone
hormone release systems
-endocrine glands can be stimulated to release hormones by nerves or other hormones
-pituitary gland often secretes hormones which affect other glands
how is the pituitary gland linked to hypothalamus?
-both located in brain
-hypothalamus often controls pituitary
how does the hypothalamus control the pituitary gland?
-hyp contains neurosecretory cells which produce secretions from axons
-group of these cells called neurosecretory cells 1 produce substances that stimulate or inhibit release of hormones from anterior pituitary
-they are known as releasing factors or release inhibiting factors
-Neurosecretory cells 2 produce secretions that are stored in the posterior pituitary and released later as hormones
all about pituitary gland
-controlled by hypothalamus
-produces 6 hormones from anterior lobe e.g. GH or TSH
-produces 2 from posterior lobe e.g. oxytocin and ADH
hormone mode 1- release of second messenger
-hormone binds to receptor on target cell membrane- may do this as they are not lipid soluble and cannot cross membrane
-triggers intracellular membrane bound reactions
-stimulates release of second messenger
-second messenger activates enzymes to alter metabolism of cell
example of second messenger
1.adrenaline binds to receptor
2.this activates enzyme called adenyl cyclase which converts ATP to cyclic AMP
3.cAMP acts as second messenger
4.it triggers diff responses in cell e.g. inc respiration and muscle contraction
exam q- Adrenaline binds to receptors in the plasma membranes of liver cells. Explain how this causes the blood glucose concentration to increase.
- Adenylate cyclase activated / cAMP
produced /
-activates enzymes in cell
-(So) glycogenolysis / gluconeogenesis
occurs / glycogenesis inhibited;