9. Lumps & Bumps II Flashcards
Where does the coloration in ocular pigmented lesions come from?
Melanocytes found in the connective tissues and basal layers.
What are the 5 classifications of ocular pigmented lesions?
Naevus, racial melanosis, ocular melanocytosis, primary acquired melanosis, conjunctival melanoma
Naevi are ...
.
They are the ...
conjunctival tumour that can be ...
in colour with ...
. Form in ...
due to ...
and ...
. They grow ...
. They are either ...
or ...
and ...
while close to the limbus. They commonly only have one or two ...
and cysts are present in ...
%.
Naevi are ‘ocular benign pigmented lesions’.
They are the most common
conjunctival tumour that can be patchy
in colour with haloing
. Form in pubescent years
due to skin stretching
and increased blood supply
. They grow very slowly
. They are either flat
or minorly elevated
and unilateral
while close to the limbus. They commonly only have one or two feeder vessels
and cysts are present in 70
%.
Naevi are classifed based on depth or cell type/appearance:
1. ...
ones are found in the ...
2. ...
ones are found in the ...
3. ...
ones are both 1 and 2
Naevi are classifed based on depth or cell type/appearance:
1. junctional
ones are found in the epithelial basal layer/stroma junction
2. intradermal
ones are found in the stroma
3. compound
ones are both 1 and 2
Congenital melanocytosis are ...
pigmented lesions.
Defined by ...
, particularly the ...
or ...
. It’s called ...
if it affects the eye alone, it’s called ...
if it affects the eye and skin. About ...
% have associated glaucoma and ...
-...
% an develop into melanoma. Can ...
or ...
at puberty.
Congenital melanocytosis are benign
pigmented lesions.
Defined by increased colour of deep tissues due to excess melanosomes
, particularly the sclera
or skin of lids
. It’s called congenital melanosis
if it affects the eye alone, it’s called Naevus of Ota
if it affects the eye and skin. About 10
% have associated glaucoma and 2
-4
% an develop into melanoma. Can change
or appear
at puberty.
Primary acquired melanosis is an ...
pigmented lesion.
Affects ...
, ...
people and looks like a ...
, ...
, ...
lesion. Can be found anywhere on ...
, but especially on the ...
. They are quite ...
. Based on ...
of melanocytic cells (like CIN), can ...
since they affect the ...
, and have minimal ...
.
Primary acquired melanosis is an ocular premalignant
pigmented lesion.
Affects middle aged
, fair skinned
people and looks like a unilateral
, diffuse
, pigmented
lesion. Can be found anywhere on conjunctiva
, but especially on the lid margins
. They are quite flat
. Based on lateral proliferation
of melanocytic cells (like CIN), can move
since they affect the conjunctiva
, and have minimal feeder vessels
.
Melanoma are ...
pigmented lesions....
% develop from primary acquired melanosis. They are ...
which means they are not ...
and often ...
. They grow ...
and have ...
coloration. They have ...
boundaries with small ...
. They have lots of ...
and can also have ...
. They are ...
.
Melanoma are ocular malignant
pigmented lesions.75
% develop from primary acquired melanosis. They are invasive
which means they are not motile over sclera
and often invade the cornea
. They grow quickly
and have dense
coloration. They have irregular
boundaries with small haloes
. They have lots of feeder vessels
and can also have hemorrhages
. They are raised
.