9 Glycolysis Questions Flashcards

1
Q

Hydrolysis of ATP has a DG°´ of -32 kJ/mol. Hydrolysis of Fruc-1,6-BP to F-6-P has a DG°´ of -14 kJ/mol. What is the standard free energy change for the reaction catalyzed by PFK-1?

A.-46 kJ/mol

B.-22 kJ/mol

C.-18 kJ/mol

D.18 kJ/mol

E.46 kJ/mol

A

A.-46 kJ/mol

B.-22 kJ/mol

C.-18 kJ/mol

D.18 kJ/mol

E.46 kJ/mol

  • ATP + H2O -> ADP + Pi + H+ delta G = -32
  • F-1,6-BP + H2O -> F-6-BP + H2O delta G = -14
    • NET
    • ATP + F6P -> ADP + F-1,6-BP + H+
      • delta G = (-32+14) = -18
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