[9] FINALS | RENAL DRUGS Flashcards
acts to increase flow of urine
DIURETICS
DIURETICS
Purpose:
* Decrease h____
* Decrease e____
Purpose:
* Decrease hypertension
* Decrease edema
DIURETICS
Drug Categories:
A. T____
B. L____
C. K____
D. C____
E. O____
Drug Categories:
A. Thiazides & Thiazide-like
B. Loop diuretics
C. K+ sparing diuretics
D. Carbonic Anhydrase inhibitor
E. Osmotic Diuretics
THIAZIDES & THIAZIDE-LIKE
EXAMPLES (2)
Chlorothiazide (Diuril), Hydrochlorothiazide (Hydrodiuril - most common)
THIAZIDES & THIAZIDE-LIKE
I: hypertension and p____
MOA: Acts on the ____ renal tubules to promote Na, Cl, and water excretion
S/E: h____ , hypomagnesemia, h____ , dizziness, headache, N&V, constipation, o____ , hyperglycemia, h____
I: hypertension and peripheral edema
MOA: Acts on the distal convoluted renal tubules to promote Na, Cl, and water excretion
S/E: Hypokalemia, hypomagnesemia, hypercalcemia, dizziness, headache, N&V, constipation, orthostatic hypotension, hyperglycemia, hyperuricemia
THIAZIDES
Nursing Considerations:
Assessment:
- VS, Weight, u____, e____
Check:
- Peripheral extremities – e____
- History of drugs and herbal supplements taken daily
- Review drug to drug interactions (d____, corticosteroids, antidiabetics, g____, l____)
Nursing Considerations:
Assessment:
- VS, Weight, Urine Output, Electrolyte values
Check:
- Peripheral extremities – Edema
- History of drugs and herbal supplements taken daily
- Review drug to drug interactions (digoxin, corticosteroids, antidiabetics, gingko, licorice)
THIAZIDES
Nursing Considerations:
✓Monitor VS (BP & Pulse) and s____ levels- report changes
✓Watch out for d____ and h____
❑ (muscle weakness, leg cramps, and cardiac
dysrhythmias)
✓Monitor daily weight- weight gain of ____ lbs. is equivalent to 1 L of body fluids
✓Note urine output (fluid loss or retention)
Nursing Considerations:
✓Monitor VS and serum electrolyte levels- report changes
✓Watch out for digitalis toxicity and hypokalemia
❑ (muscle weakness, leg cramps, and cardiac
dysrhythmias)
✓Monitor daily weight- weight gain of 2.2 lbs. is equivalent to 1 L of body fluids
✓Note urine output (fluid loss or retention)
THIAZIDES
Patient teaching:
- Emphasize adherence to the therapy plan
- Take drug e____
- Keep drugs out of reach of small children
- Inform – certain h____ may interact with
thiazide diuretics - Teach on how to take and record b____ (daily)
Patient teaching:
- Emphasize adherence to the therapy plan
- Take drug early in the morning
- Keep drugs out of reach of small children
- Inform – certain herbal products may interact with
thiazide diuretics - Teach on how to take and record BP (daily)
THIAZIDES
Patient teaching:
- Prevent o____ - by slowly changing position from lying to standing
- Use sunblock – to prevent p____
- Eat foods rich in p____ (e.g. avocado, banana) - supplements may be prescribed
- Taken with f____ - to avoid GI upset (diarrhea, N/V, anorexia)
Patient teaching:
- Prevent orthostatic hypotension - by slowly changing position from lying to standing
- Use sunblock – to prevent photosensitivity
- Eat foods rich in Potassium (e.g. avocado, banana) - supplements may be prescribed
- Taken with FOOD- to avoid GI upset (diarrhea, N/V, anorexia)
LOOP DIURETICS/ HIGH CEILING
EXAMPLES (2)
Furosemide (Lasix - most common), Bumetanide (Bumex)
LOOP DIURETICS/ HIGH CEILING
I: E____ and hypertension
MOA: Acts on the a____ by inhibiting Na reabsorption
S/E: H____, Na, Ca, Mg, Cl, dizziness, headache, N&V, o____
I: Edema and hypertension
MOA: Acts on the ascending loop of Henle by inhibiting Na reabsorption
S/E: Hypokalemia, Na, Ca, Mg, Cl, dizziness, headache, N&V, orthostatic hypotension
LOOP DIURETICS/ HIGH CEILING
Assessment:
- Check for drugs that may cause drug interaction (e.g. alcohol, a____, anticoagulants, corticosteroids, l____, a____, digitalis)
- VS, serum electrolytes, weight, and UO
- Note hypersensitivity to s____
Assessment:
- Check for drugs that may cause drug interaction (e.g. alcohol, aminoglycosides, anticoagulants, corticosteroids, lithium, amphotericin B, digitalis)
- VS, serum electrolytes, weight, and UO
- Note hypersensitivity to sulfonamides
LOOP DIURETICS/ HIGH CEILING
Nursing Considerations:
- Monitor VS (decrease B____) and UO (should be at least ____ mL/h or ____ mL/24 hr)
- Notify doctor – if UO does not increase (s____ may be present)
- Weigh the patient - A loss of ____ lbs is equivalent to a fluid loss of 1 L
Nursing Considerations:
- Monitor VS (decrease BP) and UO (should be at least 30 mL/h or 600 mL/24 hr)
- Notify doctor – if UO does not increase (severe renal disorder may be present)
- Weigh the patient - A loss of 2.2 lbs is equivalent to a fluid loss of 1 L
LOOP DIURETICS/ HIGH CEILING
Nursing Considerations:
- Administer IV f____ SLOWLY
- h____ may occur if it is rapidly injected
- Check for signs of h____ (< 3.5 mEq/L) - Muscles weakness, abdominal distention, leg cramps, or cardiac dysrhythmias
- Taken in the m____
- Rise slowly from lying to standing (dizziness resulting from fluid loss)
Nursing Considerations:
- Administer IV furosemide SLOWLY
- Hearing loss may occur if it is rapidly injected
- Check for signs of hypokalemia (< 3.5 mEq/L) - Muscles weakness, abdominal distention, leg cramps, or cardiac dysrhythmias
- Taken in the morning
- Rise slowly from lying to standing (dizziness resulting from fluid loss)
OSMOTIC DIURETIC
EXAMPLES (2)
Mannitol (Osmitrol - most common), Urea (Ureaphil)
OSMOTIC DIURETIC
I: Increased i____, i____ and prevent k____
MOA: Increases p____ and b____ concentration in renal tubules
S/E:
✓ F____ imbalance
✓ Pulmonary Edema
✓ N&V
✓ T____
✓ A____
I: Increased IOP, ICP and prevent kidney failure
MOA: Increases plasma and blood concentration in renal tubules
S/E:
✓ F&E imbalance
✓ Pulmonary Edema
✓ N&V
✓ Tachycardia
✓ Acidosis
OSMOTIC DIURETIC
Nursing Consideration for Mannitol
- Mannitol c____ at low temperature
-use i____
-may be warmed
-f____ drip
-give with extreme caution if with h____
Nursing Consideration for Mannitol
- Mannitol CRYSTALLIZES at low temperature
-use in-line filter
-may be warmed
-fast drip
-give with extreme caution if with heart condition/ heart failure
CARBONIC ANHYDRASE INHIBITORS
EXAMPLE (1)
Acetazolamide (Diamox)