[9] Chronic Kidney Disease Flashcards
1
Q
G1 Stage of CKD has a GFR of?
A
> = 90
2
Q
G2 Stage of CKD has a GFR of?
A
60-89
3
Q
A1 Classification of CKD has a A:C ratio of?
A
<30 mg/g
4
Q
A2 Classification of CKD has a A:C ratio of?
A
30-300 mg/g
5
Q
A3 Classification of CKD has a A:C ratio of?
A
> 300 mg/g
6
Q
“Key Players” in Bone and Mineral Disease in CKD
A
FGF23
Parathyroid Hormone
Vitamin D
7
Q
Effect of FGF23 in the Kidney
A
Stimulate phosphaturia by down-regulating luminal expression of Na-PO3 co-transporter in the PCT
Directly inhibits renal 1-a hydroxylase to reduce systemic levels of 1,25-dihydroxyvitamin D
8
Q
How does downregulating Vitamin D affect Phosphate levels?
A
Decreased intestinal absorption of phosphate
