[7] Pathology of Glomerular Disease

Question 1

Most common cause of Glomerular Disease in Children

Answer 1

Minimal Change Disease

Question 2

Most common cause of Glomerular Disease in Adults

Answer 2

Membranous

Question 3

Most Typical Type of Change in Glomerular Disease

Answer 3

Stage II Subepithelial Deposits

Question 4

How do you differentiate the different MPGN Types?

Answer 4

Type I: Massive subendothelial deposits +/- mesangial deposits

Type II: Large electron-dense deposits in intramembranous portion

Type III: Subepithelial deposits, segmental GBM fragmentation

Question 5

Light Microscopy Changes in MPGN

Answer 5

Proliferative, mesangial matrix increase

Tram-tracking, capillary wall thickening

Question 6

Immunofluorescence Changes in MPGN

Answer 6

C3 in the GDM and Mesangium

Question 7

Other name for IgA Nephropathy

Answer 7

Berger’s Disease

Question 8

Confirmation of Diagnosis of IgA Nephropathy is done by?

Answer 8

IF: Intense Mesangial Granular IgA