[9] Calcium, Magnesium, and Phosphorous Balance Flashcards
Calcium % in Soft Tissue
0.6%
Calcium % in Bone and Teeth
99.3% as Hydroxyapatite
Calcium % in ECF
0.1%
What does Calcium bind with in the cell?
Clabindin D-28K
Remember: Calcium cannot exist as a free form in the cell
How is Calcium removed from the cell?
Ca2+ ATPase Pump
How does Vitamin D help in calcium Absorption
Synthesis of Calbindin D-28K
Protein-Bound Calcium
90% Bound to Albumin
10% Globulin
How do you correct total calcium levels
Add 0.8mg/dL for every 1g/dL if albumin is <4g/dL
Formula for Serum Calcium
Adjusted Total Calcium = Total Calcium + (0.8 * (4- Albumin))
Effect of Blood pH on Free Serum Calcium
Acidemia
Alkalemia
Acid: + Ionized Ca2+
Alkal: - Ionized Ca2+
Low Serum Calcium immediate activates?
PTH
Function: Phosphorous
Skeletal Development
Mineral Metabolism
Energy Transfer through Mitochondrial Metabolism
Cell Membrane Phospholipid Content and Function
Cell Signalling
Platelet Aggregation
Relationship of Calcium and Phosphorous
Inverse, like a see-saw
What does Vitamin D do for Phosphorous?
Promotes Reabsorption
Where is Phosphorous Absorbed?
70% PCT
15% Straight segment of the promixal tubule