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Oral Path Exam 2 > 9: Allergies/Immunologic Diseases > Flashcards

9: Allergies/Immunologic Diseases Flashcards

1
Q

Elevated painful fungivform papillae often red, white or yellow in color with unknown etiology resolving on their own

A

Transient Lingual papillitis

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2
Q

This is a common oral mucosal pathoses that is caused by different things in different people, characterized by a large ulcer on nonkeratinized mucosa

A

Aphthous ulcer/Aphthous stomatitis/recurrent aphthous ulcer (RAU)

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3
Q

Layman’s term for Recurrent Aphthous ulcer(RAU)

A

Canker sore

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4
Q

7 factors that can contribute to Recurrent Aphthous Ulcer (RAU)

A

Allergies, Genetics, Nutritional deficiency, Hematologic abnormalities, Hormones, Trauma, Stress

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5
Q

9 systemic disorders associated with Recurrent Aphthous Ulcer (RAU)

A

Bechet’s Syndrome (ocular/orogenital lesions), Celiac disease (Gluten sensitivity in Small intestine), Cyclic neutropenia (cyclic low neutrophils ~21 days), Nutritional deficiencies, IgA deficiency, Immunocompromised, IBD, Reiter’s Syndrome (inflammatory arthritis, conjunctivitis, urethritis/cervicitis), Sweet’s syndrome (febrile neutrophilic dermatosis)

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6
Q

3 Clinical variations of aphthous ulcer

A

Minor 80% Major 10%

Herpetiform 10%

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7
Q

Aphthous ulcer variation with fewest recurrences, shortest duration, 1-5 lesions buccal and labial mucosa, but very painful?

A

Minor aphthous

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8
Q

Longest duration aphthous ulcer taking 2-6 weeks to heal, 1-10 lesions, labial mucosa, soft palate, tonsillar fauces, may cause scaring?

A

Major Aphthous

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9
Q

Aphthous ulcer with the most frequent recurrence, greatest number of lesion, up to 100?

A

Herpetiform Aphthous ulcers

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10
Q

If see HerpetiformAphthous ulcer, what should be done with medical history?

A

review med history to rule out underlying systemic disorder

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11
Q

2 drugs to treat Herpetiform Aphthous ulcer?

A

topical corticosteroids

Injections of triamcinolone acetonide

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12
Q

Tx for all 3 Aphthous type ulcers?

A

steroids

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13
Q

Multisystem disorder with oral, genital, or ocular lesions, always having oral lesions at some point, looking like aphthous ulcers?

A

Behcet’s syndrome

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14
Q

What is required to diagnose Bechet’s Syndrome

A

Recurrent oral ulcers w/ two of the following: Recurrent genital ulcers
Eye lesions, Skin lesions, Positive pathergy

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15
Q

What is positive pathergy associated with Bechet’s Syndrome?

A

Skin reaction to the injection of sterile saline

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16
Q

Where do aphthous ulcers associated with Behcet’s Syndrome appear orally?

A

Soft palate and oropharynz

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17
Q

Tx for Bechet’s Syndrome aphthous ulcers?

A

Topical or intralesional corticosteroids or oral colchicines or dapsone

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18
Q

Multisystem granulomatous disorder of unknown etiology?

A

Sarcoidosis

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19
Q

What race is more affected by Sarcoidosis?

A

Blacks, 10-17 times more than whites

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20
Q

2 age range peaks for Sarcoidosis?

A

25-35, 45-65

21
Q

What system is always involved in Sarcoidosis?

A

Lymph

22
Q

Sarcoidosis lesions that appear frequently on the nose, ear, lips, and face that are chronic, violaceous (violet color), indurated?

A

Lupus pernio

23
Q

Sarcoidosis lesions that are scattered, nonspecific tender erythematous nodules, frequently occurring on the lower legs?

A

Erythema nodosum

24
Q

What causes Sarcoid lesions?

A

Noncaseating granulomas

25
Q

2 syndromes associated with Sarcoidosis

A

Lofgren’s syndrome & Heerfordt’s syndrome

26
Q

Character of Lofgren’s Syndrome (2)?

A

Erythema nodosum (sarcoid), Bilateral hilar lymphadenopathy (sarcoid), Arthralgia (joint pain)

27
Q

Character of Heerfordt’s Syndrome (good board question) (5)?

A

Uveo-parotid fever, Parotid enlargement, Anterior uveitis (eye inflammation), Facial paralysis, and Fever

28
Q

This is a trashcan disorder that is diagnosed by the exclusion of other disorders. It’s character is nonspecific granulomatous inflammation.

A

Orofacial granulomatosis

29
Q

What 4 other granuloma diseases must be ruled out before diagnosing Orofacial Granulomatosis?

A

Sarcoidosis, Crohn’s disease (form of irritable disease), Fungus infection, Foreign body reaction

30
Q

Orofacial granulomatosis + Facial paralysis + fissured tongue (board question)

A

Melkersson-Rosenthal Syndrome

31
Q

Allergic reaction of the oral mucosa to the systemic administration of a medication?

A

Stomatitis medicamentosa

32
Q

2 best things to do when person comes in with highly ulcerated mouth?

A

List of meds, when they started taking each one, and how long the ulcers have been there

33
Q

Allergic contact stomatitis caused by what and is prevalent in which gender?

A

Diverse topical agents; Female predilection

34
Q

Acute Allergic Contact stomatitis symptoms (3)?

A

Burning (Itching/stinging/tingling), Redness, Edema

35
Q

Chronic Allergic Contact stomatitis symptoms (3)?

A

Erythematous, white/hyperkeratotic, erosions in affected zone

36
Q

4 ways to treat Allergic Contact stomatitis?

A

Remove suspected allergen, antihistamine therapy, topical anesthetic (dyclonine HCl), topical corticosteroids (fluocinonide gel or
dexamethasone elixir)

37
Q

Unique inflammatory skin disease that involves the circumoral area?

A

Perioral dermatitis

38
Q

What exacerbates perioral dermatitis?

A

Topical corticosteroid application

39
Q

Tx of perioral dermatitis?

A

Metronidazole

40
Q

What is a risk of cinnamon flavoring?

A

Contact stomatitis on gingiva

41
Q

What does cinnamon flavor induced contact stomatitis resemble?

A

Plasma cell gingivitis (irradescent red gingivitis)

42
Q

When there is a hypersensitivity to a dental metal, what metal is it?

A

Mercury

43
Q

Lichenoid lesion only in the area of a dental material?

A

Lichenoid contact stomatitis

44
Q

Hypersensitivity reactions to dental metals disappear after how many days once metal is removed?

A

10-14 days

45
Q

Most commonly affected sites for Lichenoid contact stomatitis?

A

Posterior buccal mucosa, ventral surface of lateral border of the tongue

46
Q

Diffuse edematous swelling of the soft tissues that most commonly involves the subcutaneous and submucosal connective tissues but may affect the GI or respiratory tract, occasionally fatal?

A

Angioedema/Quincke’s disease

47
Q

Most common cause of Angioedema

A

Mast cell degranulation causing histamine release

48
Q

2 ways to treat angioedema?

A

PO antihistamine and IM Epinephrine

Oral Path Exam 2 (8 decks)

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