88 - Salivary Glands Flashcards

1
Q

Major salivary glands

A

Parotid
Mandibular
Sublingual
Zygomatic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Minor salivary glans

A

Tonsillar
Labial
Lingual
Molar
Palatine
Buccal

Molar in cats only - Well developed

To Live Life, Must Pass Boards!

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q
A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

6 functions of saliva

A
  • Lubricate bolus
  • Thermoregulation
  • Oral cavity cleansing
  • Buffer weak acids
  • Protect the epithelium
  • Reduce bacterial growth

Salivary amylase plays no significant role in digestion in dogs and cats

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

How is saliva produced and transported from the gland?

A

Produced in acinus
Serous and mucin producing cells
Flows into intercalated duct which coalesce

Intralobular => Interlobular => Lobular => Lobar => Major excretory duct

Mandibular and parotid mainly serous
Zygomatic and sublingual mainly mucinous

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

How is saliva processed before excretion?

A

Phase one =
* Produced in acinus
* Acinar cells absorb Na+
* Water drawn in creating Na rich saliva
* Flows into collecting ducts

Phase two =
* Active resorption of Na
* Secretion of Bicarb and Potassium within the intralobular duct epithelium
* Resultant saliva is Bicarb and Potassium rich

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

How is saliva production mediated?

A

Autonomic control

Parasympathetic stimulation
- vasodilation
- upregulation of cyclic guanosine monophosphate (cGMP) which directly upregulates acinar production of saliva

Sympathetic downregulation
- Minor inhibition of flow by causing contraction of myoepithelial cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Which nerves provide parasympathetic supply to the salivary glands?

A

FACIAL NERVE

MANDIBULAR NERVE

Mandibular n = largest branch of the trigmeminal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Which structures surround the parotid salivary gland?

(Muscular, neural, vascular?)

A

Caudally:
* Sternomastoid m
* Cleidocervicalis m

Cranial:
* Masseter m

Ventral:
* Mandibular salivary gland

Superficial:
* Platysma
* Parotidoauricularis

Deep:
* Auricular cartilage of ear

Neurovascular
* Facial nerve
* Maxillary and temporal arteries
* Internal maxillary vein

CHALLENGING DISSECTION

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Where does the parotid duct travel?

Where is the papilla?

A

2-3 ductules exit
Ventrorostral to the gland
Lateral and ventral to masseter

Papilla = 4th Upper Premolar (Carnassial tooth)

Accessory gland is dorsal to the duct and empties into main duct

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Blood supply to the parotid?

A

Parotid a

=> Branch of the external carotid

(Sits medial to the gland, ventral to ear canal)

Venous drainage =>
Greater auricular and temporal veins

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Where is the zygomatic gland located?

How many ducts are there?

Where is the major papilla for the zygomatic duct?

A

Located ventral and rostrolateral to the globe

1 major and 4 minor ducts

Enters the vestibule 1cm caudal to the parotid papilla at the level of the last upper molar

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What is the blood supply to the zygomatic salivary gland?

A

Infraorbital artery

Deep facial vein

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Where does the mandibular salivary gland sit?

Which structures surround it?

A

Sits caudomedial to the angle of the mandible

Gland lies medial to the linguofacial and maxillary vein junction (External Jugular bifurcation)

Mandibular LN ventral to the gland

Medial retropharyngeal and larynx medial to the gland

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

How is the mandibular salivary gland related to the sublingual gland?

A

Shares a common capsule

forms the

‘Mandibular sublingual salivary gland complex’

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Where does the mandibular salivary duct run?

Where does the papilla sit?

A

Exits medial surface of the gland

Runs medial to the sublingual gland
Horizontal to mandibular ramus

Runs between the styloglossus and myelohyoideus muscles

Enters at the sublingual caruncle
(lateral to the frenulum)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What is the blood supply to the mandibular salivary gland

A

Glandular branch of the facial a.

Lingual vein

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

What are the two portions of the sublingual gland?

A

Monostomatic
- Shared capsule with the mandibular gland
- Tapers to triangular shape rostrally
- Loose clusters sitting deep to the digastricus and myelohyoideus

Polystomatic
- Small clusters ROSTRAL to the LINGUAL NERVE
- Empty directly into the oral cavity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Where doe the sublingual duct enter the oral cavity

A

At the sublingual caruncle
Just caudal to the mandibular papilla

Note the duct courses with the mandibular duct, but they are seperate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Blood supply for the sublingual?

A

Glandular branch of the facial artery
(Monostomatic portion as part of MDSLGC)

Sublingual branch of the lingual artery
(Polystomatic portion)

Venous drainage = satellites of the arterial supply

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Which lymph nodes do each gland drain to?

A

All drain to the medial retropharnygeal

Parotid also drains to the parotid LN

22
Q

Which two salivary gland diseases are considered non-surgical

A

Sialoadenitis

Necrotising sialometaplasia

23
Q

Presentation for sialoadenitis?

A

BILATERAL non-inflammatory, non-neoplastic sialoadenitis

Cx = Retching, gulping, lip smacking, hypersalivation, weight loss

24
Q

Treatment for sialadenitis

A
  • Exclude other disease
  • Glucocorticoids
  • Antibioitcs
  • PHENOBARBITONE (1-2 MG/KG PO BID)
  • Sialoadenectomy (considered non-surgical)

Linked to limbic epilepse
Cause unknown

25
Q

Which breeds have presented with necrotising sialometaplasia?

What concurrent abormalities are detected?

Speculated causes?

A

Terrier breeds

Oesophageal and GI disease

Vagal hyperstimulation vs Limbic epilepsy

Necrosis, ductal hypertrophy, infarction, squamous metaplasia on histo

26
Q

Treatment for necrotising sialometaplasia?

A

Phenobarb

Address underlying disease

Inconsistent response to medical and surgical management

27
Q

Which breeds are predisposed to sialocoeles?

A

Poodles
GSD
Australian Silky
Daxies

28
Q

Speculated causes of sialocoeles?

A

Trauma (neck leads)
Foreign body
Neoplasia
Sialoliths

29
Q

How is sialocoele diagnosed?

A

Viscous, honey coloured, blood tinged fluid on aspirate

Cytology: Non-degenerate neuts, foamy macs, pink-volet mucin
PERIODIC ACID-SCHIFF stain = mucin specific

Imaging: CT, MRI, Sialography, US

30
Q

Give one major DDx for Sialocoele

A

BRANCHIAL CLEFT CYST

31
Q

Name the four different types of sialocoele

A

Cervical
Zygomatic
Pharyngeal
Ranula

32
Q

What is the most common type of sialocoele?

How do they present?

A

Cervical

Cranioventral cervical swelling

(Can be difficult to differential which side)

33
Q

Presenting signs for zygomatic sialocoele

A

Exophthalmos
TEL protrusion
Painless orbital swelling
Ventral deviation at papilla (last upper molar)

34
Q

Presenting signs for pharyngeal sialocoele?

Which breed are over-represented for these?

A

Swelling caudal, dorsal or lateral
Stridor or respiratory distress

Miniature poodles

(Males > Females)

35
Q

Presenting signs for sublingual sialocoeles?

A

RANULA

Medial tongue deviation
Dysphagia, difficulty with prehension

36
Q

Name one non-surgical treatment for sialocoele

A

Injection of a sclerosing agent

37
Q

Describe the surgical technique for Zygomatic Sialoadenectomy

A
  • Approach to the dorsal zygomatic arch
  • Reflection of the masseter aponeurosis from ventral arch
  • Reflection of orbital fascia from dorsal arch
  • Zygomatic ostectomy
  • Blunt dissection of the gland
  • Dorsal retraction to visualise and ligate infraortbital a blood supply
38
Q

Describe the approach for parotid sialoadenectomy

Common complication?

A
  • Incision from ventral to acoustic meatus to caudal mandible
  • Skin, subcut, platysma, parotidoauricularis incised
  • Identification and division of caudal auricular vein
  • Gland dissected at dorsocranial border and continued rostrally to visulise ear canal
  • Care to spare the facial nerve at the level of the horizontal ear canal
  • Cauterise small medial vessels during dissection
  • Dissected out to level of the duct, ligated and divided.
  • Check lateral cheek swelling may be due to accessory parotid gland involvement
  • Minimise deadspace through closure of superficial muscles, subcut and skin

Facial nerve paresis

39
Q

Describe the surgical treatment for ranulas

A

Mandibular and sublingual sialoadenectomy
Plus MARSUPIALISATION

  • Large oval shpaed full thickness region of the ranula excised
  • External oral mucosa sutured to the sialocoele lining
  • Mucosal margin can be hemmed inwards to prevent exposed edges healing over
40
Q

How should pharyngeal sialocoeles be treated?

A

Aspiration or drainage via the oropharynx to stabilise

Resect reduntant tissue

Marsupialisation PLUS
Mandibular and sublingual sialoadenectomy

42% have concurrent mandib/sublingual cervical sialocoele

41
Q

What are the two approaches for excision of the mandibular and sublingual salivary glands?

Which method is preferred?

A

**Ventral **

Lateral

Ventral preferred!!

42
Q

Describe the ventral approach for mandibular and sublingual sialoadenectomy

A

Incision =
* 4-5cm to caudal to margin of mandibular ramus
* Extending rostrally towards mandibular physis
* Midline if bilateral needed
* Incision through subcut, skin and platysma

Identification =
* Identify jugular bifurcation (maxillary and linguofacial veins)
* Mandibular gland immediately cranial to bifurcation (mandibular LN ventral and retropharyngeal medial to it)
* Capsule exposed with blunt dissection and incised
* Medial vessels ligated
* Complex caudally retracted to allow dissection of sublingual gland dorsal to digastricus
* Haemostat placed from rostral to caudal under the digastricus
* Duct clamped and transected to remove gland complex
* Ducts pulled under the digastricus and dissection continued rostrally
* Mylohyoideus incised for rostral exposure if needed
* CONTINUE DISSECTION TO THE LEVEL OF THE LINGUAL NERVE
* If ranula present, dissect to level of sublingual caruncle

Lingual nerve = end of the monostomatic complex
Remaining should drain into oral cavity directly

43
Q

Describe the lateral approach to the mandibular/sublingual gland complex

A

Lateral recumbency, affected side up, neck extended

  • Jugular bifurcation identified
  • Horizontal incision over mandibular gland between linguofacial and maxillary vein
  • Capsule exposed bluntly, incised and emptied of mucocoele
  • Blood supply ligated and dissection continued rostrally parallel with ducts
  • Ducts ligated or separated with slow/steady traction
  • Transected ends accessed medially and rostrally to the digastricus and dissectio continued
44
Q

Which duct is predominantly affected by sialoliths?

A

Parotid

(Also reported in mandibular/sublingual)

45
Q

Clinical signs of sialoliths?

A

Swelling of the lateral aspect of the face

Dx on palpation, rads or CT

46
Q

What are sialoliths composed of?

A

Calcium oxalate
Phosphate
Magnesium
Carbonate
Ammonium
Proteinaceous material

47
Q

How are sialoliths treated?

A
  • Sialoadenectomy (Mandibular/sublingual)
  • Duct resection and anastomosis
  • Incision and second intention healing of the duct (if close to the papilla)
  • Marsupialisation into oral cavity (if duct dilation is primary concern)
48
Q

What salivary tumours have been reported?

Which glands are more commonly affected?

A

Tumours
- Adenocarcinoma
- Acicic carcinoma

Location
- Mandibular
- Parotid

49
Q

How do salivary carcinomas tend to behave

A

Local invasion into surrounding tissues
Mets to LN
Distant mets less common

Met rate in cats = 39% local, 16% distant
Met rate in dogs = 17% local, 8% distant

50
Q

Treatment for salivary neoplasia?

A

Aggressive cytoreduction of gross disease
LN extirpation
+/- Adjuvant therapy

51
Q

MST for salivary neoplasia?

Prognostic factor

A

74-550d

Disease stage is prognostic