8.1 Nerve And Glial Cells

Question 1

Number of neurons and glial cells in the human body

Answer 1

10^11

10 times more glial cells

Question 2

Neurons structure

Answer 2

Body (soma), dendrites, 1xaxon

Question 3

How does myelin helps faster conductance?

Answer 3

Lipid insulator!

Increase memb. Resistance -> forces current to flow along the axon interior

Question 4

Which nerve is faster- large/small nerve, and why?

Answer 4

Large is faster. Resistance is inertly prop. to cross sectional area

Question 5

What is the difference btw. Astrocytes and neurons resting memb. Potential?

Answer 5

In astrocytes it is more negative

Question 6

Which glial cell produce myelin and where?

Answer 6

Oligodendrocytes (CNS)

Schwann (PNS)

Question 7

Approximate resting memb. Pot. In astrocytes=

Answer 7

-85mV

Question 8

What is the AMPA receptor?

Answer 8

Ionotropic Glu R

Permeable to univalent cations (Na influx)

Question 9

What is NMDA R?

Answer 9

Ionotropic Glu R

Permeable to univalent cations (Na influx)+Ca2 ions

Question 10

What is required for the opening of NMDA R?

Answer 10

Depol.

Question 11

Glu R types (2)

Answer 11

Ionotropic (NMDA, AMPA)

Metabotropic (7TM, M1-M5)

Question 12

What is usually the cause of IPSP (not the NT)

Answer 12

Opening of ligand gated Cl ions

Opening of K channels

Question 13

Types of GABA R (2)?

Answer 13

GABA (A)- ligand gated Cl channel

GABA (B)- 7TM (Gi GPCR -> opening of K channels)