8 - Synaptic Transmission and Drug Effects Flashcards
At resting potential, which chemicals can pass freely through the membrane?
Water, oxygen and carbon dioxide
What are the major excitatory neurotransmitters?
Acetylcholine, glutamate, norepinephrine
What are the major inhibitory neurotransmitters?
Dopamine, GABA, gylcine, serotonin
What is the most common excitatory neurotransmitter in the brain?
Glutamate
What is the most common inhibitory neurotransmitter in the brain?
GABA
What happens if post-synaptic activation slightly opens sodium gates?
Depolarization
What happens if post-synaptic activation slightly opens calcium gates?
Hyperpolarizatoin
In what area do must addictive drugs stimulate dopamine release?
Nucleus accumbens
Otto Loewi won the Nobel Prize in 1936 for his discovery of?
The chemical nature of neurotransmission