8 - Chronic Enteropathy Flashcards
Clinical manifestations for chronic enteropathy in cats
Weight loss and changes in appetite
Chronic enteropathy you have to rule out what metabolic causes
Hepatic or renal disease, pancreatitis, endocrine diseases
Most prevalent chronic enteropathy cause
Food responsive enteropathy
PLE definition
Small intestinal malabasorptive syndrome characterized by excessive protein loss
PLE is not typically seen in
Cats
3 Pathophysiology of PLE
Increased mucosal permeability,mechanical causes, lymphatic obstruction or rupture
Mechanical causes of PLE include
GI ulcers, worms, RHF, intussusception
Lymphatic obstruction or rupture causing PLE include
Lymphangiectasia
PLE in dogs are most often associated with
Lymphoplasmacytic enteritis followed by lymphangiectasia
Breeds predisposed to PLE
Yorker, border collie, GS, Rottweiler, terrier
Clinical presentation of PLE
Small intestinal diarrhea, weight loss, panyhypoproteinemia, hypercoaguable, edema
Lymphangiectasia is a type of
PLE
Clinical presentation of lymphangiectasia
Panhypoproteinemia, decreased cholesterol, striation on ultrasound
Predisposed to lymphangiectasia
Yorker
Lymphangiectasia are at risk of
Vitamin D deficiency
Treatment for lymphangiectasia
Low fat diet is the most importnat intervention
Always confirm hypocalcemia with
Ionized calcium
Goals of abdominal ultrasound
Screen for underlying disease and asses teh GI tract and lymph nodes
With chronic eneteropathy, the small intestine may appear how on ultrasound
Thickened
Intestines that measure thickened do not tule in
Chronic enteropathy
What can be more concerning on abdominal utlrasound for chronic enteropathy
Loss of normal layering
What on ultrasound increase suspicion of lymphangiectasia
Mucosal hyperchoic striations perpendicular to the lumen
Check folate for
Duodenal malabospriove
Check cobalamin for what absorption
Ileal malabsroptuve disease
Cobalamin supplementation recommended when cobalamine is
Less than 400
Options for deworming
Fenbendazole, Drontal plus, profender
Topical cat wormer
Profender
Problem with endoscopy for chronic enteropathy
All looks the same
Patients in which biopsies may be indicated earlier
Hyporexic, anorexic, weight loss, low albumin, boxer, loss of wall layering
Surgical biopsy for
Jejunum
Endoscopy upper GI
Gastric, duodenal
Lower GI scope
Colon, ileum
Most common intestinal neoplasia
Intestinal adenocarcinoma and GI lymphoma
Treatment of choice for adenocarcinoma
Surgery